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Research Article

Hybrids of the bHLH and bZIP Protein Motifs Display Different DNA-Binding Activities In Vivo vs. In Vitro

  • Hiu-Kwan Chow,

    Affiliation: Department of Chemistry, University of Toronto, Mississauga, Ontario, Canada

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  • Jing Xu,

    Affiliation: Department of Chemistry, University of Toronto, Mississauga, Ontario, Canada

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  • S. Hesam Shahravan,

    Affiliation: Department of Chemistry, University of Toronto, Mississauga, Ontario, Canada

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  • Antonia T. De Jong,

    Affiliation: Department of Chemistry, University of Toronto, Mississauga, Ontario, Canada

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  • Gang Chen,

    Affiliation: Department of Chemistry, University of Toronto, Mississauga, Ontario, Canada

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  • Jumi A. Shin mail

    jumi.shin@utoronto.ca

    Affiliations: Department of Chemistry, University of Toronto, Mississauga, Ontario, Canada, Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, Ontario, Canada

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  • Published: October 24, 2008
  • DOI: 10.1371/journal.pone.0003514

About the Authors

Hiu-Kwan Chow, Jing Xu, S. Hesam Shahravan, Antonia T. De Jong, Gang Chen, Jumi A. Shin
Department of Chemistry, University of Toronto, Mississauga, Ontario, Canada
Jumi A. Shin
Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, Ontario, Canada

Corresponding Author

Email: jumi.shin@utoronto.ca

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: HKC JX JAS. Performed the experiments: HKC JX SHS ADJ GC. Analyzed the data: HKC SHS ADJ. Wrote the paper: HKC SHS GC JAS.