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Research Article

Serum and Cerebrospinal Fluid Autoantibodies in Patients with Neuropsychiatric Lupus Erythematosus. Implications for Diagnosis and Pathogenesis

  • Hilda Fragoso-Loyo,

    Affiliation: Department of Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, México, Distrito Federal, México

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  • Javier Cabiedes,

    Affiliation: Department of Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, México, Distrito Federal, México

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  • Alejandro Orozco-Narváez,

    Affiliation: Department of Neurology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, México, Distrito Federal, México

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  • Luis Dávila-Maldonado,

    Affiliation: Department of Neurology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, México, Distrito Federal, México

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  • Yemil Atisha-Fregoso,

    Affiliation: Department of Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, México, Distrito Federal, México

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  • Betty Diamond,

    Affiliation: The Feinstein Institute for Medical Research, Manhasset, New York, United States of America

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  • Luis Llorente,

    Affiliation: Department of Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, México, Distrito Federal, México

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  • Jorge Sánchez-Guerrero mail

    jsanchezguerrero7@gmail.com

    Affiliation: Department of Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, México, Distrito Federal, México

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  • Published: October 06, 2008
  • DOI: 10.1371/journal.pone.0003347

About the Authors

Hilda Fragoso-Loyo, Javier Cabiedes, Yemil Atisha-Fregoso, Luis Llorente, Jorge Sánchez-Guerrero
Department of Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, México, Distrito Federal, México
Alejandro Orozco-Narváez, Luis Dávila-Maldonado
Department of Neurology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, México, Distrito Federal, México
Betty Diamond
The Feinstein Institute for Medical Research, Manhasset, New York, United States of America

Corresponding Author

Email: jsanchezguerrero7@gmail.com

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: HEFL JC LDM BD LL JSG. Performed the experiments: HEFL JC AON LDM YAF BD LL JSG. Analyzed the data: HEFL JC AON LDM YAF BD LL JSG. Contributed reagents/materials/analysis tools: JC BD LL JSG. Wrote the paper: HEFL JC AON LDM YAF BD LL JSG.