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Research Article

MUC1* Mediates the Growth of Human Pluripotent Stem Cells

  • Sherry T. Hikita,

    Affiliations: Center for Stem Cell Biology and Engineering, University of California Santa Barbara, Santa Barbara, California, United States of America, Department of Molecular, Cellular and Developmental Biology, University of California Santa Barbara, Santa Barbara, California, United States of America

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  • Kenneth S. Kosik,

    Affiliations: Center for Stem Cell Biology and Engineering, University of California Santa Barbara, Santa Barbara, California, United States of America, Department of Molecular, Cellular and Developmental Biology, University of California Santa Barbara, Santa Barbara, California, United States of America, Neuroscience Research Institute, University of California Santa Barbara, Santa Barbara, California, United States of America

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  • Dennis O. Clegg,

    Affiliations: Center for Stem Cell Biology and Engineering, University of California Santa Barbara, Santa Barbara, California, United States of America, Department of Molecular, Cellular and Developmental Biology, University of California Santa Barbara, Santa Barbara, California, United States of America, Neuroscience Research Institute, University of California Santa Barbara, Santa Barbara, California, United States of America

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  • Cynthia Bamdad mail

    cbamdad@minervabio.com

    Affiliation: Minerva Biotechnologies, Waltham, Massachusetts, United States of America

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  • Published: October 03, 2008
  • DOI: 10.1371/journal.pone.0003312

About the Authors

Sherry T. Hikita, Kenneth S. Kosik, Dennis O. Clegg
Center for Stem Cell Biology and Engineering, University of California Santa Barbara, Santa Barbara, California, United States of America
Sherry T. Hikita, Kenneth S. Kosik, Dennis O. Clegg
Department of Molecular, Cellular and Developmental Biology, University of California Santa Barbara, Santa Barbara, California, United States of America
Kenneth S. Kosik, Dennis O. Clegg
Neuroscience Research Institute, University of California Santa Barbara, Santa Barbara, California, United States of America
Cynthia Bamdad
Minerva Biotechnologies, Waltham, Massachusetts, United States of America

Corresponding Author

Email: cbamdad@minervabio.com

Competing Interests

Drs. Kosik and Bamdad are shareholders in Minerva Biotechnologies.

Author Contributions

Conceived and designed the experiments: KSK CCB. Performed the experiments: STH. Analyzed the data: STH KSK DC CCB. Contributed reagents/materials/analysis tools: CCB. Wrote the paper: CCB. Sole or lead inventor on the novel target MUC1*, antibodies and methods to manipulate cancer and stem cell growth by manipulating the MUC1* receptor: CCB.