On Evaluating MHC-II Binding Peptide Prediction Methods

Yasser EL-Manzalawy; Drena Dobbs; Vasant Honavar

doi:10.1371/journal.pone.0003268

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Open Access

Peer-reviewed

Research Article

On Evaluating MHC-II Binding Peptide Prediction Methods

Yasser EL-Manzalawy ,

* E-mail: yasser@iastate.edu

Affiliation Department of Computer Science, Center for Computational Intelligence, Learning, and Discovery, Iowa State University, Ames, Iowa, United States of America
⨯
Drena Dobbs,

Affiliation Department of Genetics, Development and Cell Biology, Bioinformatics and Computational Biology Graduate Program, Center for Computational Intelligence, Learning and Discovery, Iowa State University, Ames, Iowa, United States of America
⨯
Vasant Honavar

Affiliation Department of Computer Science, Center for Computational Intelligence, Learning, and Discovery, Iowa State University, Ames, Iowa, United States of America
⨯

On Evaluating MHC-II Binding Peptide Prediction Methods

Yasser EL-Manzalawy,
Drena Dobbs,
Vasant Honavar

Published: September 24, 2008
https://doi.org/10.1371/journal.pone.0003268

About the Authors

Yasser EL-Manzalawy

* E-mail: yasser@iastate.edu

Affiliation Department of Computer Science, Center for Computational Intelligence, Learning, and Discovery, Iowa State University, Ames, Iowa, United States of America

Drena Dobbs

Affiliation Department of Genetics, Development and Cell Biology, Bioinformatics and Computational Biology Graduate Program, Center for Computational Intelligence, Learning and Discovery, Iowa State University, Ames, Iowa, United States of America

Vasant Honavar

Affiliation Department of Computer Science, Center for Computational Intelligence, Learning, and Discovery, Iowa State University, Ames, Iowa, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: YEM. Performed the experiments: YEM. Analyzed the data: YEM DD VH. Contributed reagents/materials/analysis tools: YEM DD VH. Wrote the paper: YEM DD VH.

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Forecasting
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Major histocompatibility complex
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Statistical data
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Kernel methods
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Sequence alignment
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Machine learning
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Binders
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Database and informatics methods
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