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Research Article

Changes in Cognition and Mortality in Relation to Exercise in Late Life: A Population Based Study

  • Laura E. Middleton,

    Affiliation: Geriatric Medicine Research Unit, Centre for Health Care of the Elderly, Halifax, Nova Scotia, Canada

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  • Arnold Mitnitski,

    Affiliation: Geriatric Medicine Research Unit, Centre for Health Care of the Elderly, Halifax, Nova Scotia, Canada

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  • Nader Fallah,

    Affiliation: Geriatric Medicine Research Unit, Centre for Health Care of the Elderly, Halifax, Nova Scotia, Canada

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  • Susan A. Kirkland,

    Affiliation: Department of Community Health and Epidemiology, Dalhousie University, Halifax, Nova Scotia, Canada

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  • Kenneth Rockwood mail

    kenneth.rockwood@dal.ca

    Affiliation: Geriatric Medicine Research Unit, Centre for Health Care of the Elderly, Halifax, Nova Scotia, Canada

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  • Published: September 01, 2008
  • DOI: 10.1371/journal.pone.0003124

About the Authors

Laura E. Middleton, Arnold Mitnitski, Nader Fallah, Kenneth Rockwood
Geriatric Medicine Research Unit, Centre for Health Care of the Elderly, Halifax, Nova Scotia, Canada
Susan A. Kirkland
Department of Community Health and Epidemiology, Dalhousie University, Halifax, Nova Scotia, Canada

Corresponding Author

Email: kenneth.rockwood@dal.ca

Competing Interests

In the last 5 years, Kenneth Rockwood has received speaking and/or consulting fees from Glaxo Smith Kline, Janssen Ortho, Lundbeck, Merck, Myriad, Novartis, Numico and Pfizer and holds a research grant from Janssen, through the Canadian Institutes of Health Research Research and Development program. He is President and majority shareholder of DementiaGuide, Inc., a web-based symptom guide for people with dementia. Our work includes no data on medications or dementia symptoms. Dr. Mitnitski, Dr. Kirkland, and Ms. Middleton have no conflicts of interest.

Author Contributions

Conceived and designed the experiments: LEM KR. Analyzed the data: LEM. Contributed reagents/materials/analysis tools: KR. Wrote the paper: LEM SAK KR. Senior investigator of the CSHA, collected data and supervised local data collection at each wave: KR. Secured funding for the study and these analyses: KR. Drafted various aspects of the paper: KR. Conducted the analyses: LEM. Verified the analyses and developed procedures for model adjustment: ABM NF. Read and approved the final version of the manuscript: KR LEM ABM NF SAK.