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Research Article

Leptin Replacement Improves Cognitive Development

  • Gilberto J. Paz-Filho,

    Affiliations: Department of Psychiatry and Behavioral Sciences, Center for Pharmacogenomics, University of Miami Miller School of Medicine, Miami, Florida, United States of America, SEMPR – Serviço de Endocrinologia e Metabologia da UFPR, Curitiba, Parana, Brazil

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  • Talin Babikian,

    Affiliation: Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine at University of California Los Angeles, Los Angeles, California, United States of America

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  • Robert Asarnow,

    Affiliation: Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine at University of California Los Angeles, Los Angeles, California, United States of America

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  • Karin Esposito,

    Affiliation: Department of Psychiatry and Behavioral Sciences, Center for Pharmacogenomics, University of Miami Miller School of Medicine, Miami, Florida, United States of America

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  • Halil K. Erol,

    Affiliation: Department of Psychiatry and Behavioral Sciences, Center for Pharmacogenomics, University of Miami Miller School of Medicine, Miami, Florida, United States of America

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  • Ma-Li Wong,

    Affiliation: Department of Psychiatry and Behavioral Sciences, Center for Pharmacogenomics, University of Miami Miller School of Medicine, Miami, Florida, United States of America

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  • Julio Licinio mail

    jlicinio@med.miami.edu

    Affiliation: Department of Psychiatry and Behavioral Sciences, Center for Pharmacogenomics, University of Miami Miller School of Medicine, Miami, Florida, United States of America

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  • Published: August 29, 2008
  • DOI: 10.1371/journal.pone.0003098

About the Authors

Gilberto J. Paz-Filho, Karin Esposito, Halil K. Erol, Ma-Li Wong, Julio Licinio
Department of Psychiatry and Behavioral Sciences, Center for Pharmacogenomics, University of Miami Miller School of Medicine, Miami, Florida, United States of America
Gilberto J. Paz-Filho
SEMPR – Serviço de Endocrinologia e Metabologia da UFPR, Curitiba, Parana, Brazil
Talin Babikian, Robert Asarnow
Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine at University of California Los Angeles, Los Angeles, California, United States of America

Corresponding Author

Email: jlicinio@med.miami.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: GPF TB RA KE MLW JL. Performed the experiments: GPF TB RA KE HKE MLW JL. Analyzed the data: GPF TB RA KE MLW JL. Contributed reagents/materials/analysis tools: RA MLW JL. Wrote the paper: GPF TB RA KE MLW JL.