About the Authors

Nathan T. Morrell

Contributed equally to this work with: Nathan T. Morrell, Philipp Leucht

Affiliation Division of Plastic and Reconstructive Surgery, Department of Surgery, Stanford University, Stanford, California, United States of America

Philipp Leucht

Contributed equally to this work with: Nathan T. Morrell, Philipp Leucht

Affiliation Division of Plastic and Reconstructive Surgery, Department of Surgery, Stanford University, Stanford, California, United States of America

Ludan Zhao

Affiliation Division of Plastic and Reconstructive Surgery, Department of Surgery, Stanford University, Stanford, California, United States of America

Jae-Beom Kim

Affiliation Division of Plastic and Reconstructive Surgery, Department of Surgery, Stanford University, Stanford, California, United States of America

Derk ten Berge

Affiliation Department of Developmental Biology, School of Medicine, Stanford University, Stanford, California, United States of America

Karthik Ponnusamy

Affiliation Division of Plastic and Reconstructive Surgery, Department of Surgery, Stanford University, Stanford, California, United States of America

A. Lyonel Carre

Affiliation Division of Plastic and Reconstructive Surgery, Department of Surgery, Stanford University, Stanford, California, United States of America

Henryk Dudek

Affiliation Curis Inc., Cambridge, Massachusetts, United States of America

Marie Zachlederova

Affiliation Curis Inc., Cambridge, Massachusetts, United States of America

Michael McElhaney

Affiliation Curis Inc., Cambridge, Massachusetts, United States of America

Shirley Brunton

Affiliation Evotec Ltd., Abingdon, Oxon, United Kingdom

Janet Gunzner

Affiliation Department of Medicinal Chemistry, Genentech Inc., South San Francisco, California, United States of America

Marinella Callow

Affiliation Department of Cancer Targets, Genentech Inc., South San Francisco, California, United States of America

Paul Polakis

Affiliation Department of Cancer Targets, Genentech Inc., South San Francisco, California, United States of America

Mike Costa

Affiliation Department of Cancer Targets, Genentech Inc., South San Francisco, California, United States of America

Xiaoyan M. Zhang

Affiliation Curis Inc., Cambridge, Massachusetts, United States of America

Jill A. Helms

rnusse@stanford.edu (RN), jhelms@stanford.edu (JAH)

Affiliation Division of Plastic and Reconstructive Surgery, Department of Surgery, Stanford University, Stanford, California, United States of America

Roel Nusse

rnusse@stanford.edu (RN), jhelms@stanford.edu (JAH)

Affiliation Department of Developmental Biology, School of Medicine, Stanford University, Stanford, California, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: NTM PL MC XMZ JAH RN. Performed the experiments: NTM PL LZ JBK DtB KP ALC HD MZ MM SB JG MC. Analyzed the data: NTM PL JBK DtB HD MZ MM SB JG MC PP MC XMZ JAH RN. Contributed reagents/materials/analysis tools: PP MC XMZ RN. Wrote the paper: PL JAH.