About the Authors

Johnathon R. Walls

Contributed equally to this work with: Johnathon R. Walls, Leigh Coultas

Affiliations Mouse Imaging Centre (MICe), Hospital for Sick Children, Toronto Centre for Phenogenomics, Toronto, Ontario, Canada, Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada

Leigh Coultas

Contributed equally to this work with: Johnathon R. Walls, Leigh Coultas

Affiliation Hospital for Sick Children Research Institute, Developmental and Stem Cell Biology Program, Toronto, Ontario, Canada

Janet Rossant

Affiliations Hospital for Sick Children Research Institute, Developmental and Stem Cell Biology Program, Toronto, Ontario, Canada, Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada

R. Mark Henkelman

mhenkel@phenogenomics.ca

Affiliations Mouse Imaging Centre (MICe), Hospital for Sick Children, Toronto Centre for Phenogenomics, Toronto, Ontario, Canada, Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada

Competing Interests

JRW and RMH are named as inventors and co-applicants with the Hospital for Sick Children on a patent application “Resolution Improvement in Emission Optical Projection Tomography” PCT/CA2007/001637.

Author Contributions

Conceived and designed the experiments: JRW RMH. Performed the experiments: JRW LC. Analyzed the data: JRW LC. Wrote the paper: JRW LC JR RMH.