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Research Article

Gene Expression and Functional Studies of the Optic Nerve Head Astrocyte Transcriptome from Normal African Americans and Caucasian Americans Donors

  • Haixi Miao,

    Affiliation: Department of Ophthalmology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, United States of America

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  • Lin Chen,

    Affiliation: Department of Ophthalmology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, United States of America

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  • Sean M. Riordan,

    Affiliation: Department of Ophthalmology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, United States of America

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  • Wenjun Li,

    Affiliation: Department of Ophthalmology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, United States of America

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  • Santiago Juarez,

    Affiliation: Department of Ophthalmology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, United States of America

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  • Andrea M. Crabb,

    Affiliation: Department of Ophthalmology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, United States of America

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  • Thomas J. Lukas,

    Affiliation: Department of Molecular Pharmacology and Biological Chemistry, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, United States of America

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  • Pan Du,

    Affiliation: Robert H, Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, United States of America

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  • Simon M. Lin,

    Affiliation: Robert H, Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, United States of America

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  • Alexandria Wise,

    Affiliation: Department of Biology, City College of New York, New York, New York, United States of America

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  • Olga A. Agapova,

    Affiliation: Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St. Louis, Missouri, United States of America

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  • Ping Yang,

    Affiliation: Department of Pediatrics, Washington University School of Medicine, St. Louis, Missouri, United States of America

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  • Charles C. Gu,

    Affiliation: Division of Biostatistics, Washington University School of Medicine, St. Louis, Missouri, United States of America

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  • M. Rosario Hernandez mail

    m-hernandez-neufeld@northwestern.edu

    Affiliation: Department of Ophthalmology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, United States of America

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  • Published: August 06, 2008
  • DOI: 10.1371/journal.pone.0002847

About the Authors

Haixi Miao, Lin Chen, Sean M. Riordan, Wenjun Li, Santiago Juarez, Andrea M. Crabb, M. Rosario Hernandez
Department of Ophthalmology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, United States of America
Thomas J. Lukas
Department of Molecular Pharmacology and Biological Chemistry, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, United States of America
Pan Du, Simon M. Lin
Robert H, Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, United States of America
Alexandria Wise
Department of Biology, City College of New York, New York, New York, United States of America
Olga A. Agapova
Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St. Louis, Missouri, United States of America
Ping Yang
Department of Pediatrics, Washington University School of Medicine, St. Louis, Missouri, United States of America
Charles C. Gu
Division of Biostatistics, Washington University School of Medicine, St. Louis, Missouri, United States of America

Corresponding Author

Email: m-hernandez-neufeld@northwestern.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: MRH. Performed the experiments: HM LC SMR WL SJ AMC AW OAA PY. Analyzed the data: PD SML CG. Wrote the paper: HM TL MRH.