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Research Article

Fibronectin Unfolding Revisited: Modeling Cell Traction-Mediated Unfolding of the Tenth Type-III Repeat

  • Elaine P. S. Gee,

    Affiliation: Graduate Program in Biophysics, Harvard University, Cambridge, Massachusetts, United States of America

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  • Donald E. Ingber,

    Affiliations: Graduate Program in Biophysics, Harvard University, Cambridge, Massachusetts, United States of America, Department of Surgery, Vascular Biology Program, Children's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America, Department of Pathology, Vascular Biology Program, Children's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

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  • Collin M. Stultz mail

    cmstultz@csail.mit.edu

    Affiliations: Graduate Program in Biophysics, Harvard University, Cambridge, Massachusetts, United States of America, Department of Electrical Engineering and Computer Science, Research Laboratory of Electronics, Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

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  • Published: June 11, 2008
  • DOI: 10.1371/journal.pone.0002373

About the Authors

Elaine P. S. Gee, Donald E. Ingber, Collin M. Stultz
Graduate Program in Biophysics, Harvard University, Cambridge, Massachusetts, United States of America
Donald E. Ingber
Department of Surgery, Vascular Biology Program, Children's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America
Donald E. Ingber
Department of Pathology, Vascular Biology Program, Children's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America
Collin M. Stultz
Department of Electrical Engineering and Computer Science, Research Laboratory of Electronics, Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

Corresponding Author

Email: cmstultz@csail.mit.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: DI CS. Performed the experiments: EG. Analyzed the data: DI CS EG. Contributed reagents/materials/analysis tools: EG. Wrote the paper: DI CS EG.