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Research Article

A Combination of Nutriments Improves Mitochondrial Biogenesis and Function in Skeletal Muscle of Type 2 Diabetic Goto–Kakizaki Rats

  • Weili Shen,

    Affiliation: Institute for Nutritional Science, Shanghai Institutes of Biological Sciences, Chinese Academy of Sciences, Shanghai, China

    X
  • Jiejie Hao,

    Affiliations: Institute for Nutritional Science, Shanghai Institutes of Biological Sciences, Chinese Academy of Sciences, Shanghai, China, Graduate School of the Chinese Academy of Sciences, Beijing, China

    X
  • Chuan Tian,

    Affiliations: Institute for Nutritional Science, Shanghai Institutes of Biological Sciences, Chinese Academy of Sciences, Shanghai, China, Graduate School of the Chinese Academy of Sciences, Beijing, China

    X
  • Jinmin Ren,

    Affiliation: Institute for Nutritional Science, Shanghai Institutes of Biological Sciences, Chinese Academy of Sciences, Shanghai, China

    X
  • Lu Yang,

    Affiliation: Institute for Nutritional Science, Shanghai Institutes of Biological Sciences, Chinese Academy of Sciences, Shanghai, China

    X
  • Xuesen Li,

    Affiliations: Institute for Nutritional Science, Shanghai Institutes of Biological Sciences, Chinese Academy of Sciences, Shanghai, China, Graduate School of the Chinese Academy of Sciences, Beijing, China

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  • Cheng Luo,

    Affiliation: Institute for Nutritional Science, Shanghai Institutes of Biological Sciences, Chinese Academy of Sciences, Shanghai, China

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  • Carl W. Cotma,

    Affiliation: Institute for Brain Aging and Dementia, University of California Irvine, Irvine, California, United States of America

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  • Jiankang Liu mail

    j.liu@uci.edu

    Affiliation: Institute for Brain Aging and Dementia, University of California Irvine, Irvine, California, United States of America

    X
  • Published: June 04, 2008
  • DOI: 10.1371/journal.pone.0002328

About the Authors

Weili Shen, Jiejie Hao, Chuan Tian, Jinmin Ren, Lu Yang, Xuesen Li, Cheng Luo
Institute for Nutritional Science, Shanghai Institutes of Biological Sciences, Chinese Academy of Sciences, Shanghai, China
Jiejie Hao, Chuan Tian, Xuesen Li
Graduate School of the Chinese Academy of Sciences, Beijing, China
Carl W. Cotma, Jiankang Liu
Institute for Brain Aging and Dementia, University of California Irvine, Irvine, California, United States of America

Corresponding Author

Email: j.liu@uci.edu

Competing Interests

Patent has been filed on combination of mitochondrial nutrients metioned in this paper: Chinese patent application No 200610162888.4. The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: CC JL WS. Performed the experiments: WS JR JH CT LY XL CL. Analyzed the data: WS JH CT. Wrote the paper: JL WS.