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Research Article

Automated Nuclear Analysis of Leishmania major Telomeric Clusters Reveals Changes in Their Organization during the Parasite's Life Cycle

  • Fernando de M. Dossin equal contributor,

    equal contributor Contributed equally to this work with: Fernando de M. Dossin, Alexandre Dufour, Elodie Dusch

    Affiliation: Systems Biology of Pathogens Group, Institut Pasteur Korea, Seoul, South Korea

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  • Alexandre Dufour equal contributor,

    equal contributor Contributed equally to this work with: Fernando de M. Dossin, Alexandre Dufour, Elodie Dusch

    Affiliation: Image Mining Group, Institut Pasteur Korea, Seoul, South Korea

    Current address: Quantitative Image Analysis, Institut Pasteur, Paris, France.

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  • Elodie Dusch equal contributor,

    equal contributor Contributed equally to this work with: Fernando de M. Dossin, Alexandre Dufour, Elodie Dusch

    Affiliation: Image Mining Group, Institut Pasteur Korea, Seoul, South Korea

    X
  • Jair L. Siqueira-Neto,

    Affiliation: Systems Biology of Pathogens Group, Institut Pasteur Korea, Seoul, South Korea

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  • Carolina B. Moraes,

    Affiliations: Systems Biology of Pathogens Group, Institut Pasteur Korea, Seoul, South Korea, Departamento de Microbiologia, Imunologia e Parasitologia, Universidade Federal de São Paulo, São Paulo, Brazil

    X
  • Gyong Seon Yang,

    Affiliation: Systems Biology of Pathogens Group, Institut Pasteur Korea, Seoul, South Korea

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  • Maria Isabel Cano,

    Affiliation: Departamento de Genética, Instituto de Biociências, Universidade Estadual Paulista, Botucatu, São Paulo, Brazil

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  • Auguste Genovesio,

    Affiliation: Image Mining Group, Institut Pasteur Korea, Seoul, South Korea

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  • Lucio H. Freitas-Junior mail

    junior@ip-korea.org

    Affiliation: Systems Biology of Pathogens Group, Institut Pasteur Korea, Seoul, South Korea

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  • Published: June 11, 2008
  • DOI: 10.1371/journal.pone.0002313

About the Authors

Fernando de M. Dossin, Jair L. Siqueira-Neto, Carolina B. Moraes, Gyong Seon Yang, Lucio H. Freitas-Junior
Systems Biology of Pathogens Group, Institut Pasteur Korea, Seoul, South Korea
Alexandre Dufour, Elodie Dusch, Auguste Genovesio
Image Mining Group, Institut Pasteur Korea, Seoul, South Korea
Carolina B. Moraes
Departamento de Microbiologia, Imunologia e Parasitologia, Universidade Federal de São Paulo, São Paulo, Brazil
Maria Isabel Cano
Departamento de Genética, Instituto de Biociências, Universidade Estadual Paulista, Botucatu, São Paulo, Brazil

Corresponding Author

Email: junior@ip-korea.org

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: AG LF FD JS MC. Performed the experiments: FD AD ED CM GY. Analyzed the data: LF FD AD ED JS CM. Contributed reagents/materials/analysis tools: LF. Wrote the paper: LF FD AD JS CM.