About the Authors
- Jamie L. Barger
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Affiliation LifeGen Technologies, LLC, Madison, Wisconsin, United States of America
- Tsuyoshi Kayo
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Affiliation LifeGen Technologies, LLC, Madison, Wisconsin, United States of America
- James M. Vann
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Affiliations Department of Medical Genetics, University of Wisconsin, Madison, Wisconsin, United States of America, Department of Genetics, University of Wisconsin, Madison, Wisconsin, United States of America
- Edward B. Arias
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Affiliation Division of Kinesiology, University of Michigan, Ann Arbor, Michigan, United States of America
- Jelai Wang
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Affiliation Section on Statistical Genetics, Department of Biostatistics, University of Alabama at Birmingham, Birmingham, Alabama, United States of America
- Timothy A. Hacker
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Affiliation Department of Medicine, University of Wisconsin-Madison, Madison, Wisconsin, United States of America
- Ying Wang
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Affiliation R&D Human Nutrition and Health, DSM Nutritional Products Ltd., Basel, Switzerland
- Daniel Raederstorff
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Affiliation R&D Human Nutrition and Health, DSM Nutritional Products Ltd., Basel, Switzerland
- Jason D. Morrow
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Affiliations Department of Pharmacology, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America, Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America
- Christiaan Leeuwenburgh
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Affiliation Department of Aging and Geriatrics and College of Medicine, University of Florida, Gainesville, Florida, United States of America
- David B. Allison
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Affiliation Section on Statistical Genetics, Department of Biostatistics and Clinical Nutrition Research Center, University of Alabama at Birmingham, Birmingham, Alabama, United States of America
- Kurt W. Saupe
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Affiliation Department of Medicine, University of Wisconsin-Madison, Madison, Wisconsin, United States of America
- Gregory D. Cartee
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Affiliation Division of Kinesiology, University of Michigan, Ann Arbor, Michigan, United States of America
- Richard Weindruch
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* E-mail: rhweindr@wisc.edu (RW); taprolla@wisc.edu (TP)
Affiliation Department of Medicine and Veterans Administration Hospital, University of Wisconsin-Madison, Madison, Wisconsin, United States of America
- Tomas A. Prolla
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* E-mail: rhweindr@wisc.edu (RW); taprolla@wisc.edu (TP)
Affiliations Department of Medical Genetics, University of Wisconsin, Madison, Wisconsin, United States of America, Department of Genetics, University of Wisconsin, Madison, Wisconsin, United States of America
Competing Interests
T.A. Prolla and R. Weindruch are founders and board directors of LifeGen Technologies, LLC, a company focused on the use of gene expression profiling to understand the mechanisms of action of caloric restriction.
Author Contributions
Conceived and designed the experiments: TP RW. Performed the experiments: TK JV EA TH. Analyzed the data: TP JW RW JB. Contributed reagents/materials/analysis tools: DA JW GC CL KS YW DR JM. Wrote the paper: TP RW JB.