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Research Article

Regulation of Epithelial Branching Morphogenesis and Cancer Cell Growth of the Prostate by Wnt Signaling

  • Bu-Er Wang,

    Affiliation: Department of Molecular Biology, Genentech, Inc., South San Francisco, California, United States of America

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  • Xi-De Wang,

    Affiliation: Department of Molecular Biology, Genentech, Inc., South San Francisco, California, United States of America

    Current address: Clinical Discovery, Bristol-Myers Squibb, Princeton, New Jersey, United States of America

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  • James A. Ernst,

    Affiliation: Department of Protein Chemistry and Protein Engineering, Genentech, Inc., South San Francisco, California, United States of America

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  • Paul Polakis,

    Affiliation: Department of Cancer Target and Pathways, Genentech, Inc., South San Francisco, California, United States of America

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  • Wei-Qiang Gao mail

    gao@gene.com

    Affiliation: Department of Molecular Biology, Genentech, Inc., South San Francisco, California, United States of America

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  • Published: May 14, 2008
  • DOI: 10.1371/journal.pone.0002186

About the Authors

Bu-Er Wang, Xi-De Wang, Wei-Qiang Gao
Department of Molecular Biology, Genentech, Inc., South San Francisco, California, United States of America
James A. Ernst
Department of Protein Chemistry and Protein Engineering, Genentech, Inc., South San Francisco, California, United States of America
Paul Polakis
Department of Cancer Target and Pathways, Genentech, Inc., South San Francisco, California, United States of America

Corresponding Author

Email: gao@gene.com

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: WG BW XW. Performed the experiments: BW. Analyzed the data: WG BW XW PP. Contributed reagents/materials/analysis tools: JE. Wrote the paper: WG BW XW. Other: Supervised the entire project: WG. Provided important input and suggestions: PP.