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Research Article

Efficient Array-Based Identification of Novel Cardiac Genes through Differentiation of Mouse ESCs

  • Ronald A. Miller,

    Affiliations: Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

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  • Nicolas Christoforou,

    Affiliation: Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

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  • Jonathan Pevsner,

    Affiliations: McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America, Kennedy Krieger Institute, Baltimore, Maryland, United States of America

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  • Andrew S. McCallion mail,

    amccalli@jhmi.edu (AM); gearhart@jhmi.edu (JG)

    Affiliations: McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America, Department of Molecular and Comparative Pathobiology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

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  • John D. Gearhart mail

    amccalli@jhmi.edu (AM); gearhart@jhmi.edu (JG)

    Affiliations: Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America, Department of Obstetrics and Gynecology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

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  • Published: May 14, 2008
  • DOI: 10.1371/journal.pone.0002176

About the Authors

Ronald A. Miller, Nicolas Christoforou, John D. Gearhart
Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
Ronald A. Miller, Jonathan Pevsner, Andrew S. McCallion, John D. Gearhart
McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
Jonathan Pevsner
Kennedy Krieger Institute, Baltimore, Maryland, United States of America
John D. Gearhart
Department of Obstetrics and Gynecology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
Andrew S. McCallion
Department of Molecular and Comparative Pathobiology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: JG AM RM NC. Performed the experiments: AM RM. Analyzed the data: JP RM. Contributed reagents/materials/analysis tools: JG JP NC. Wrote the paper: JG AM RM.