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Research Article

Gene Expression Profiling of Human Decidual Macrophages: Evidence for Immunosuppressive Phenotype

  • Charlotte Gustafsson mail,

    charlotte.gustafsson@imk.liu.se

    Affiliation: Division of Clinical Immunology, Unit for Autoimmunity and Immune Regulation (AIR), Department of Clinical and Experimental Medicine, Faculty of Health Sciences, University Hospital, Linköping, Sweden

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  • Jenny Mjösberg,

    Affiliation: Division of Clinical Immunology, Unit for Autoimmunity and Immune Regulation (AIR), Department of Clinical and Experimental Medicine, Faculty of Health Sciences, University Hospital, Linköping, Sweden

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  • Andreas Matussek,

    Affiliation: Department of Clinical Microbiology, County Hospital Ryhov, Jönköping, Sweden

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  • Robert Geffers,

    Affiliation: Mucosal Immunity, Helmholtz Centre for Infection Research (HCI), Braunschweig, Germany

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  • Leif Matthiesen,

    Affiliation: Division of Gynecology and Obstetrics, Faculty of Health Sciences, University Hospital, Linköping, Sweden

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  • Göran Berg,

    Affiliation: Division of Gynecology and Obstetrics, Faculty of Health Sciences, University Hospital, Linköping, Sweden

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  • Surendra Sharma,

    Affiliations: Department of Pediatrics, Brown University and Women and Infants' Hospital of Rhode Island, Providence, Rhode Island, United States of America, Department of Pathology, Brown University and Women and Infants' Hospital of Rhode Island, Providence, Rhode Island, United States of America

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  • Jan Buer,

    Affiliation: Institute of Medical Microbiology, University Hospital Essen, Essen, Germany

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  • Jan Ernerudh

    Affiliation: Division of Clinical Immunology, Unit for Autoimmunity and Immune Regulation (AIR), Department of Clinical and Experimental Medicine, Faculty of Health Sciences, University Hospital, Linköping, Sweden

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  • Published: April 30, 2008
  • DOI: 10.1371/journal.pone.0002078

About the Authors

Charlotte Gustafsson, Jenny Mjösberg, Jan Ernerudh
Division of Clinical Immunology, Unit for Autoimmunity and Immune Regulation (AIR), Department of Clinical and Experimental Medicine, Faculty of Health Sciences, University Hospital, Linköping, Sweden
Andreas Matussek
Department of Clinical Microbiology, County Hospital Ryhov, Jönköping, Sweden
Robert Geffers
Mucosal Immunity, Helmholtz Centre for Infection Research (HCI), Braunschweig, Germany
Leif Matthiesen, Göran Berg
Division of Gynecology and Obstetrics, Faculty of Health Sciences, University Hospital, Linköping, Sweden
Surendra Sharma
Department of Pediatrics, Brown University and Women and Infants' Hospital of Rhode Island, Providence, Rhode Island, United States of America
Surendra Sharma
Department of Pathology, Brown University and Women and Infants' Hospital of Rhode Island, Providence, Rhode Island, United States of America
Jan Buer
Institute of Medical Microbiology, University Hospital Essen, Essen, Germany

Corresponding Author

Email: charlotte.gustafsson@imk.liu.se

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: CG JM AM LM GB JE. Performed the experiments: RG CG JM AM. Analyzed the data: RG SS CG JM AM JE. Contributed reagents/materials/analysis tools: RG JB CG JM AM LM GB JE. Wrote the paper: CG. Other: Revision of manuscript: LM GB SS JB RG. Drafting of the manuscript: JE AM JM.