The Septins Function in G1 Pathways that Influence the Pattern of Cell Growth in Budding Yeast

Thea A. Egelhofer; Judit Villén; Derek McCusker; Steven P. Gygi; Douglas R. Kellogg

doi:10.1371/journal.pone.0002022

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Open Access

Peer-reviewed

Research Article

The Septins Function in G1 Pathways that Influence the Pattern of Cell Growth in Budding Yeast

Thea A. Egelhofer,

Affiliation Department of Molecular, Cell and Developmental Biology, University of California Santa Cruz, Santa Cruz, California, United States of America
⨯
Judit Villén,

Affiliation Department of Cell Biology, Taplin Biological Mass Spectrometry Facility, Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Derek McCusker,

Affiliation Department of Molecular, Cell and Developmental Biology, University of California Santa Cruz, Santa Cruz, California, United States of America
⨯
Steven P. Gygi,

Affiliation Department of Cell Biology, Taplin Biological Mass Spectrometry Facility, Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Douglas R. Kellogg

*To whom correspondence should be addressed. E-mail: kellogg@biology.ucsc.edu

Affiliation Department of Molecular, Cell and Developmental Biology, University of California Santa Cruz, Santa Cruz, California, United States of America
⨯

The Septins Function in G1 Pathways that Influence the Pattern of Cell Growth in Budding Yeast

Thea A. Egelhofer,
Judit Villén,
Derek McCusker,
Steven P. Gygi,
Douglas R. Kellogg

Published: April 23, 2008
https://doi.org/10.1371/journal.pone.0002022

About the Authors

Thea A. Egelhofer

Affiliation Department of Molecular, Cell and Developmental Biology, University of California Santa Cruz, Santa Cruz, California, United States of America

Judit Villén

Affiliation Department of Cell Biology, Taplin Biological Mass Spectrometry Facility, Harvard Medical School, Boston, Massachusetts, United States of America

Derek McCusker

Affiliation Department of Molecular, Cell and Developmental Biology, University of California Santa Cruz, Santa Cruz, California, United States of America

Steven P. Gygi

Affiliation Department of Cell Biology, Taplin Biological Mass Spectrometry Facility, Harvard Medical School, Boston, Massachusetts, United States of America

Douglas R. Kellogg

*To whom correspondence should be addressed. E-mail: kellogg@biology.ucsc.edu

Affiliation Department of Molecular, Cell and Developmental Biology, University of California Santa Cruz, Santa Cruz, California, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SG DK TE. Performed the experiments: TE. Analyzed the data: DK TE JV. Contributed reagents/materials/analysis tools: JV DM. Wrote the paper: DK TE. Other: Purified CDK1-CLN2: DM. Performed phosphorylation site mapping: SG JV.

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Phosphorylation
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Septins
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Cyclins
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Cell cycle and cell division
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Cell growth
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Polymerase chain reaction
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Glucose
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Genetic interactions
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