About the Authors

Tiago Fleming Outeiro

touteiro@fm.ul.pt (TO); pmclean@partners.org (PM)

Affiliations Alzheimer's Research Unit, MassGeneral Institute for Neurodegenerative Disease, MGH Harvard Medical School, Charlestown, Massachusetts, United States of America, Instituto de Medicina Molecular, Cell and Molecular Neuroscience Unit, Instituto de Fisiologia, Faculdade de Medicina da Universidade de Lisboa, Lisboa, Portugal

Preeti Putcha

Affiliation Alzheimer's Research Unit, MassGeneral Institute for Neurodegenerative Disease, MGH Harvard Medical School, Charlestown, Massachusetts, United States of America

Julie E. Tetzlaff

Affiliation Alzheimer's Research Unit, MassGeneral Institute for Neurodegenerative Disease, MGH Harvard Medical School, Charlestown, Massachusetts, United States of America

Robert Spoelgen

Affiliation Alzheimer's Research Unit, MassGeneral Institute for Neurodegenerative Disease, MGH Harvard Medical School, Charlestown, Massachusetts, United States of America

Mirjam Koker

Affiliation Alzheimer's Research Unit, MassGeneral Institute for Neurodegenerative Disease, MGH Harvard Medical School, Charlestown, Massachusetts, United States of America

Filipe Carvalho

Affiliation Alzheimer's Research Unit, MassGeneral Institute for Neurodegenerative Disease, MGH Harvard Medical School, Charlestown, Massachusetts, United States of America

Bradley T. Hyman

Affiliation Alzheimer's Research Unit, MassGeneral Institute for Neurodegenerative Disease, MGH Harvard Medical School, Charlestown, Massachusetts, United States of America

Pamela J. McLean

touteiro@fm.ul.pt (TO); pmclean@partners.org (PM)

Affiliation Alzheimer's Research Unit, MassGeneral Institute for Neurodegenerative Disease, MGH Harvard Medical School, Charlestown, Massachusetts, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: BH TO RS PM. Performed the experiments: TO PP JT RS MK FC. Analyzed the data: TO PP. Contributed reagents/materials/analysis tools: TO PP PM. Wrote the paper: BH TO PM.