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Research Article

Identifying Selected Regions from Heterozygosity and Divergence Using a Light-Coverage Genomic Dataset from Two Human Populations

  • Taras K. Oleksyk mail,

    *E-mail: oleksyk@ncifcrf.gov

    Affiliations: Laboratory of Genomic Diversity, National Cancer Institute at Frederick, Frederick, Maryland, United States of America, Basic Research Program, SAIC-Frederick, Inc., National Cancer Institute at Frederick, Frederick, Maryland, United States of America

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  • Kai Zhao,

    Affiliation: Laboratory of Genomic Diversity, National Cancer Institute at Frederick, Frederick, Maryland, United States of America

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  • Francisco M. De La Vega,

    Affiliation: Applied Biosystems, Foster City, California, United States of America

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  • Dennis A. Gilbert,

    Affiliation: Applied Biosystems, Foster City, California, United States of America

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  • Stephen J. O'Brien,

    Affiliation: Laboratory of Genomic Diversity, National Cancer Institute at Frederick, Frederick, Maryland, United States of America

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  • Michael W. Smith

    Affiliations: Laboratory of Genomic Diversity, National Cancer Institute at Frederick, Frederick, Maryland, United States of America, Basic Research Program, SAIC-Frederick, Inc., National Cancer Institute at Frederick, Frederick, Maryland, United States of America

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  • Published: March 05, 2008
  • DOI: 10.1371/journal.pone.0001712

About the Authors

Taras K. Oleksyk, Kai Zhao, Stephen J. O'Brien, Michael W. Smith
Laboratory of Genomic Diversity, National Cancer Institute at Frederick, Frederick, Maryland, United States of America
Taras K. Oleksyk, Michael W. Smith
Basic Research Program, SAIC-Frederick, Inc., National Cancer Institute at Frederick, Frederick, Maryland, United States of America
Francisco M. De La Vega, Dennis A. Gilbert
Applied Biosystems, Foster City, California, United States of America

Corresponding Author

Email: oleksyk@ncifcrf.gov

Competing Interests

TKO, KZ, SJO, and MWS declare that they do not have competing financial interests. FMDLV and DAG have competing financial interests.

Author Contributions

Conceived and designed the experiments: SO MS TO. Performed the experiments: TO KZ. Analyzed the data: TO KZ. Contributed reagents/materials/analysis tools: TO FD DG. Wrote the paper: SO MS TO.