Modulation of Interleukin-1 Transcriptional Response by the Interaction between VRK2 and the JIP1 Scaffold Protein

Sandra Blanco; Marta Sanz-García; Claudio R. Santos; Pedro A. Lazo

doi:10.1371/journal.pone.0001660

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Open Access

Peer-reviewed

Research Article

Modulation of Interleukin-1 Transcriptional Response by the Interaction between VRK2 and the JIP1 Scaffold Protein

Sandra Blanco,

Affiliation Programa de Oncología Traslacional, Instituto de Biología Molecular y Celular del Cáncer, Consejo Superior de Investigaciones Científicas (CSIC), Universidad de Salamanca, Salamanca, Spain
⨯
Marta Sanz-García,

Affiliation Programa de Oncología Traslacional, Instituto de Biología Molecular y Celular del Cáncer, Consejo Superior de Investigaciones Científicas (CSIC), Universidad de Salamanca, Salamanca, Spain
⨯
Claudio R. Santos,

Affiliation Programa de Oncología Traslacional, Instituto de Biología Molecular y Celular del Cáncer, Consejo Superior de Investigaciones Científicas (CSIC), Universidad de Salamanca, Salamanca, Spain
⨯
Pedro A. Lazo

*To whom correspondence should be addressed. E-mail: plazozbi@usal.es

Affiliation Programa de Oncología Traslacional, Instituto de Biología Molecular y Celular del Cáncer, Consejo Superior de Investigaciones Científicas (CSIC), Universidad de Salamanca, Salamanca, Spain
⨯

Modulation of Interleukin-1 Transcriptional Response by the Interaction between VRK2 and the JIP1 Scaffold Protein

Sandra Blanco,
Marta Sanz-García,
Claudio R. Santos,
Pedro A. Lazo

Published: February 20, 2008
https://doi.org/10.1371/journal.pone.0001660

About the Authors

Sandra Blanco

Affiliation Programa de Oncología Traslacional, Instituto de Biología Molecular y Celular del Cáncer, Consejo Superior de Investigaciones Científicas (CSIC), Universidad de Salamanca, Salamanca, Spain

Marta Sanz-García

Claudio R. Santos

Pedro A. Lazo

*To whom correspondence should be addressed. E-mail: plazozbi@usal.es

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: PL SB. Performed the experiments: SB MS CS. Analyzed the data: PL SB MS CS. Wrote the paper: PL.

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Transfection
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Protein kinase signaling cascade
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Signalosomes
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Protein interactions
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MAPK signaling cascades
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HeLa cells
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Small interfering RNA
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Phosphorylation
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