The Reelin Receptors Apoer2 and Vldlr Coordinate the Patterning of Purkinje Cell Topography in the Developing Mouse Cerebellum

Matt Larouche; Uwe Beffert; Joachim Herz; Richard Hawkes

doi:10.1371/journal.pone.0001653

Loading metrics

Open Access

Peer-reviewed

Research Article

The Reelin Receptors Apoer2 and Vldlr Coordinate the Patterning of Purkinje Cell Topography in the Developing Mouse Cerebellum

Matt Larouche,

Affiliation Genes and Development Research Group and Hotchkiss Brain Institute, Department of Cell Biology and Anatomy, Faculty of Medicine, The University of Calgary, Calgary, Alberta, Canada
⨯
Uwe Beffert,

Current address: Merck Research Labs Boston, Boston, Massachusetts, United States of America

Affiliation Department of Molecular Genetics, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America
⨯
Joachim Herz,

Affiliation Department of Molecular Genetics, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America
⨯
Richard Hawkes

*E-mail: rhawkes@ucalgary.ca

Affiliation Genes and Development Research Group and Hotchkiss Brain Institute, Department of Cell Biology and Anatomy, Faculty of Medicine, The University of Calgary, Calgary, Alberta, Canada
⨯

The Reelin Receptors Apoer2 and Vldlr Coordinate the Patterning of Purkinje Cell Topography in the Developing Mouse Cerebellum

Matt Larouche,
Uwe Beffert,
Joachim Herz,
Richard Hawkes

Published: February 27, 2008
https://doi.org/10.1371/journal.pone.0001653

About the Authors

Matt Larouche

Affiliation Genes and Development Research Group and Hotchkiss Brain Institute, Department of Cell Biology and Anatomy, Faculty of Medicine, The University of Calgary, Calgary, Alberta, Canada

Uwe Beffert

Current address: Merck Research Labs Boston, Boston, Massachusetts, United States of America

Affiliation Department of Molecular Genetics, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America

Joachim Herz

Affiliation Department of Molecular Genetics, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America

Richard Hawkes

*E-mail: rhawkes@ucalgary.ca

Affiliation Genes and Development Research Group and Hotchkiss Brain Institute, Department of Cell Biology and Anatomy, Faculty of Medicine, The University of Calgary, Calgary, Alberta, Canada

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: ML RH. Performed the experiments: ML. Analyzed the data: ML. Contributed reagents/materials/analysis tools: UB JH. Wrote the paper: UB JH ML RH.

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Purkinje cells
Is the Subject Area "Purkinje cells" applicable to this article?

Thanks for your feedback.
Cerebellum
Is the Subject Area "Cerebellum" applicable to this article?

Thanks for your feedback.
Central nervous system
Is the Subject Area "Central nervous system" applicable to this article?

Thanks for your feedback.
Immunostaining
Is the Subject Area "Immunostaining" applicable to this article?

Thanks for your feedback.
Neurons
Is the Subject Area "Neurons" applicable to this article?

Thanks for your feedback.
Heterozygosity
Is the Subject Area "Heterozygosity" applicable to this article?

Thanks for your feedback.
Cerebellar cortex
Is the Subject Area "Cerebellar cortex" applicable to this article?

Thanks for your feedback.
Phenotypes
Is the Subject Area "Phenotypes" applicable to this article?

Thanks for your feedback.