Patterns of Neurogenesis and Amplitude of Reelin Expression Are Essential for Making a Mammalian-Type Cortex

Tadashi Nomura; Masanori Takahashi; Yoshinobu Hara; Noriko Osumi

doi:10.1371/journal.pone.0001454

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Open Access

Peer-reviewed

Research Article

Patterns of Neurogenesis and Amplitude of Reelin Expression Are Essential for Making a Mammalian-Type Cortex

Tadashi Nomura,

Current address: Department of Cell and Molecular Biology, Karolinska Institute, Stockholm, Sweden

Affiliation Division of Developmental Neuroscience, Center for Translational and Advanced Animal Research (CTTAR), Tohoku University School of Medicine, Sendai, Japan
⨯
Masanori Takahashi,

Affiliation Division of Developmental Neuroscience, Center for Translational and Advanced Animal Research (CTTAR), Tohoku University School of Medicine, Sendai, Japan
⨯
Yoshinobu Hara,

Affiliations Division of Developmental Neuroscience, Center for Translational and Advanced Animal Research (CTTAR), Tohoku University School of Medicine, Sendai, Japan, Core Research for Evolutional Science and Technology, Japan Science and Technology Agency, Kawaguchi, Japan
⨯
Noriko Osumi

*To whom correspondence should be addressed. E-mail: osumi@mail.tains.tohoku.ac.jp

Affiliations Division of Developmental Neuroscience, Center for Translational and Advanced Animal Research (CTTAR), Tohoku University School of Medicine, Sendai, Japan, Core Research for Evolutional Science and Technology, Japan Science and Technology Agency, Kawaguchi, Japan
⨯

Patterns of Neurogenesis and Amplitude of Reelin Expression Are Essential for Making a Mammalian-Type Cortex

Tadashi Nomura,
Masanori Takahashi,
Yoshinobu Hara,
Noriko Osumi

Published: January 16, 2008
https://doi.org/10.1371/journal.pone.0001454

About the Authors

Tadashi Nomura

Current address: Department of Cell and Molecular Biology, Karolinska Institute, Stockholm, Sweden

Affiliation Division of Developmental Neuroscience, Center for Translational and Advanced Animal Research (CTTAR), Tohoku University School of Medicine, Sendai, Japan

Masanori Takahashi

Affiliation Division of Developmental Neuroscience, Center for Translational and Advanced Animal Research (CTTAR), Tohoku University School of Medicine, Sendai, Japan

Yoshinobu Hara

Affiliations Division of Developmental Neuroscience, Center for Translational and Advanced Animal Research (CTTAR), Tohoku University School of Medicine, Sendai, Japan, Core Research for Evolutional Science and Technology, Japan Science and Technology Agency, Kawaguchi, Japan

Noriko Osumi

*To whom correspondence should be addressed. E-mail: osumi@mail.tains.tohoku.ac.jp

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: TN. Performed the experiments: TN. Analyzed the data: TN. Contributed reagents/materials/analysis tools: MT YH. Wrote the paper: NO TN.

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Birds
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Quails
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Neurons
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Nerve fibers
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Neuron migration
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Cerebrum
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Immunostaining
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Embryonic pattern formation
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