About the Authors

Shinji L. Okitsu

Current address: Department of Immunology, The Scripps Research Institute, La Jolla, California, United States of America,

Affiliation Molecular Immunology, Swiss Tropical Institute, Basel, Switzerland

Olivier Silvie

Current address: Department of Parasitology, Heidelberg University School of Medicine, Heidelberg, Germany

Affiliation INSERM/UPMC UMR S U511, Immunobiologie Cellulaire et Moléculaire des Infections Parasitaires, Faculté de Médecine Pierre et Marie Curie, Centre Hospitalier Universitaire Pitié-Salpêtrière, Paris, France

Nicole Westerfeld

Affiliation Pevion Biotech, Bern, Switzerland

Marija Curcic

Affiliation Molecular Immunology, Swiss Tropical Institute, Basel, Switzerland

Andreas R. Kammer

Affiliation Pevion Biotech, Bern, Switzerland

Markus S. Mueller

Affiliation Molecular Immunology, Swiss Tropical Institute, Basel, Switzerland

Robert W. Sauerwein

Affiliation Department of Medical Microbiology, University Medical Centre St Radboud, Nijmegen, The Netherlands

John A. Robinson

Affiliation Institute of Organic Chemistry, University of Zurich, Zurich, Switzerland

Blaise Genton

Affiliation Molecular Immunology, Swiss Tropical Institute, Basel, Switzerland

Dominique Mazier

Affiliation INSERM/UPMC UMR S U511, Immunobiologie Cellulaire et Moléculaire des Infections Parasitaires, Faculté de Médecine Pierre et Marie Curie, Centre Hospitalier Universitaire Pitié-Salpêtrière, Paris, France

Rinaldo Zurbriggen

Affiliation Pevion Biotech, Bern, Switzerland

Gerd Pluschke

To whom correspondence should be addressed. E-mail: Gerd.Pluschke@unibas.ch

Affiliation Molecular Immunology, Swiss Tropical Institute, Basel, Switzerland

Competing Interests

GP and JAR received research and travel grants from Pevion Biotech, BG received a travel grant from Berna Biotech to attend an international meeting (unrelated to the presented clinical trial). GP, MSM JAR and RZ are named on a patent on UK-39 and AMA49-C1. ARK, NW, and RZ are employees of Pevion Biotech. All other authors report no conflicts of interest.

Author Contributions

Conceived and designed the experiments: DM BG GP NW SO MM RZ OS. Performed the experiments: AK NW SO MM OS MC. Analyzed the data: DM GP AK NW SO MM RZ OS MC. Contributed reagents/materials/analysis tools: RS JR. Wrote the paper: GP SO. Other: Wrote the first draft of the paper: SO.