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Research Article

SIRNA-Directed In Vivo Silencing of Androgen Receptor Inhibits the Growth of Castration-Resistant Prostate Carcinomas

  • Daniel Compagno equal contributor,

    equal contributor Contributed equally to this work with: Daniel Compagno, Carole Merle, Aurélie Morin

    Affiliation: CNRS, University Paris-Sud, FRE2944, Epigenetics and Cancer, Institut André Lwoff, Villejuif, France

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  • Carole Merle equal contributor,

    equal contributor Contributed equally to this work with: Daniel Compagno, Carole Merle, Aurélie Morin

    Affiliation: CNRS, University Paris-Sud, FRE2944, Epigenetics and Cancer, Institut André Lwoff, Villejuif, France

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  • Aurélie Morin equal contributor,

    equal contributor Contributed equally to this work with: Daniel Compagno, Carole Merle, Aurélie Morin

    Affiliation: CNRS, University Paris-Sud, FRE2944, Epigenetics and Cancer, Institut André Lwoff, Villejuif, France

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  • Cristèle Gilbert,

    Affiliation: CNRS, University Paris-Sud, FRE2944, Epigenetics and Cancer, Institut André Lwoff, Villejuif, France

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  • Jacques R. R. Mathieu,

    Affiliation: CNRS, University Paris-Sud, FRE2944, Epigenetics and Cancer, Institut André Lwoff, Villejuif, France

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  • Aline Bozec,

    Affiliation: INSERM U406, Lyon, France

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  • Claire Mauduit,

    Affiliation: INSERM U406, Lyon, France

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  • Mohammed Benahmed,

    Affiliation: INSERM U406, Lyon, France

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  • Florence Cabon mail

    To whom correspondence should be addressed. E-mail: fcabon@vjf.cnrs.fr

    Affiliation: CNRS, University Paris-Sud, FRE2944, Epigenetics and Cancer, Institut André Lwoff, Villejuif, France

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  • Published: October 10, 2007
  • DOI: 10.1371/journal.pone.0001006

About the Authors

Daniel Compagno, Carole Merle, Aurélie Morin, Cristèle Gilbert, Jacques R. R. Mathieu, Florence Cabon
CNRS, University Paris-Sud, FRE2944, Epigenetics and Cancer, Institut André Lwoff, Villejuif, France
Aline Bozec, Claire Mauduit, Mohammed Benahmed
INSERM U406, Lyon, France

Corresponding Author

Email: fcabon@vjf.cnrs.fr

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: FC DC CM MB AM. Performed the experiments: CG DC CM JM AB CM AM. Analyzed the data: CG FC DC CM JM AB CM MB AM. Wrote the paper: FC.