An Improved, Bias-Reduced Probabilistic Functional Gene Network of Baker's Yeast, Saccharomyces cerevisiae

Insuk Lee; Zhihua Li; Edward M. Marcotte

doi:10.1371/journal.pone.0000988

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Peer-reviewed

Research Article

An Improved, Bias-Reduced Probabilistic Functional Gene Network of Baker's Yeast, Saccharomyces cerevisiae

Insuk Lee,

Affiliation Center for Systems and Synthetic Biology, Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, Texas, United States of America
⨯
Zhihua Li,

Affiliation Center for Systems and Synthetic Biology, Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, Texas, United States of America
⨯
Edward M. Marcotte

*To whom correspondence should be addressed. E-mail: marcotte@icmb.utexas.edu

Affiliations Center for Systems and Synthetic Biology, Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, Texas, United States of America, Department of Chemistry and Biochemistry, Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, Texas, United States of America
⨯

An Improved, Bias-Reduced Probabilistic Functional Gene Network of Baker's Yeast, Saccharomyces cerevisiae

Insuk Lee,
Zhihua Li,
Edward M. Marcotte

Published: October 3, 2007
https://doi.org/10.1371/journal.pone.0000988

About the Authors

Insuk Lee

Affiliation Center for Systems and Synthetic Biology, Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, Texas, United States of America

Zhihua Li

Affiliation Center for Systems and Synthetic Biology, Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, Texas, United States of America

Edward M. Marcotte

*To whom correspondence should be addressed. E-mail: marcotte@icmb.utexas.edu

Affiliations Center for Systems and Synthetic Biology, Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, Texas, United States of America, Department of Chemistry and Biochemistry, Institute for Cellular and Molecular Biology, University of Texas at Austin, Austin, Texas, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: EM IL ZL. Performed the experiments: IL ZL. Analyzed the data: IL. Wrote the paper: EM IL.

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Biosynthesis
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Yeast
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Protein interactions
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Genetic networks
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Genome annotation
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Genetic interactions
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Microarrays
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Saccharomyces cerevisiae
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