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Research Article

Germ Line Origin and Somatic Mutations Determine the Target Tissues in Systemic AL-Amyloidosis

  • Stina Enqvist,

    Affiliation: Department of Genetics and Pathology, Uppsala University, Uppsala, Sweden

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  • Knut Sletten,

    Affiliation: Biotechnology Centre of Oslo, University of Oslo, Oslo, Norway

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  • Fred J. Stevens,

    Affiliation: Biosciences Division, Argonne National Laboratory, Argonne, Illinois, United States of America

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  • Ulf Hellman,

    Affiliation: Ludwig Institute for Cancer Research, Uppsala, Sweden

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  • Per Westermark mail

    To whom correspondence should be addressed. E-mail: Per.Westermark@genpat.uu.se

    Affiliation: Department of Genetics and Pathology, Uppsala University, Uppsala, Sweden

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  • Published: October 03, 2007
  • DOI: 10.1371/journal.pone.0000981

About the Authors

Stina Enqvist, Per Westermark
Department of Genetics and Pathology, Uppsala University, Uppsala, Sweden
Knut Sletten
Biotechnology Centre of Oslo, University of Oslo, Oslo, Norway
Fred J. Stevens
Biosciences Division, Argonne National Laboratory, Argonne, Illinois, United States of America
Ulf Hellman
Ludwig Institute for Cancer Research, Uppsala, Sweden

Corresponding Author

Email: Per.Westermark@genpat.uu.se

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: PW SE. Performed the experiments: SE KS UH. Analyzed the data: PW KS FS UH. Contributed reagents/materials/analysis tools: PW. Wrote the paper: PW SE.