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Research Article

An Expanded Set of Amino Acid Analogs for the Ribosomal Translation of Unnatural Peptides

  • Matthew C. T. Hartman,

    Affiliation: Howard Hughes Medical Institute, Department of Molecular Biology, Center for Computational and Integrative Biology, Simches Research Center, Massachusetts General Hospital, Boston, Massachusetts, United States of America

    Current address: Department of Chemistry, Massey Cancer Center, Virginia Commonwealth University, Richmond, Virginia, United States of America,

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  • Kristopher Josephson,

    Affiliation: Howard Hughes Medical Institute, Department of Molecular Biology, Center for Computational and Integrative Biology, Simches Research Center, Massachusetts General Hospital, Boston, Massachusetts, United States of America

    Current address: EMD Serono Research Institute, Rockland, Massachusetts, United States of America

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  • Chi-Wang Lin,

    Affiliation: Howard Hughes Medical Institute, Department of Molecular Biology, Center for Computational and Integrative Biology, Simches Research Center, Massachusetts General Hospital, Boston, Massachusetts, United States of America

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  • Jack W. Szostak mail

    To whom correspondence should be addressed. E-mail: szostak@molbio.mgh.harvard.edu

    Affiliation: Howard Hughes Medical Institute, Department of Molecular Biology, Center for Computational and Integrative Biology, Simches Research Center, Massachusetts General Hospital, Boston, Massachusetts, United States of America

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  • Published: October 03, 2007
  • DOI: 10.1371/journal.pone.0000972

About the Authors

Matthew C. T. Hartman, Kristopher Josephson, Chi-Wang Lin, Jack W. Szostak
Howard Hughes Medical Institute, Department of Molecular Biology, Center for Computational and Integrative Biology, Simches Research Center, Massachusetts General Hospital, Boston, Massachusetts, United States of America

Corresponding Author

Email: szostak@molbio.mgh.harvard.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: JS MH KJ CL. Performed the experiments: MH KJ CL. Analyzed the data: JS MH KJ CL. Wrote the paper: JS MH.