An All-Atom Model of the Chromatin Fiber Containing Linker Histones Reveals a Versatile Structure Tuned by the Nucleosomal Repeat Length

Hua Wong; Jean-Marc Victor; Julien Mozziconacci

doi:10.1371/journal.pone.0000877

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Peer-reviewed

Research Article

An All-Atom Model of the Chromatin Fiber Containing Linker Histones Reveals a Versatile Structure Tuned by the Nucleosomal Repeat Length

Hua Wong,

Affiliation Laboratoire de Physique Théorique de la Matière Condensée, Université Pierre et Marie Curie, Paris, France
⨯
Jean-Marc Victor,

Affiliation Laboratoire de Physique Théorique de la Matière Condensée, Université Pierre et Marie Curie, Paris, France
⨯
Julien Mozziconacci

*To whom correspondence should be addressed. E-mail: pipo@lptmc.jussieu.fr

Affiliations Laboratoire de Physique Théorique de la Matière Condensée, Université Pierre et Marie Curie, Paris, France, Cell Biology and Biophysics, European Molecular Biology Laboratory, Heidelberg, Germany
⨯

An All-Atom Model of the Chromatin Fiber Containing Linker Histones Reveals a Versatile Structure Tuned by the Nucleosomal Repeat Length

Hua Wong,
Jean-Marc Victor,
Julien Mozziconacci

Published: September 12, 2007
https://doi.org/10.1371/journal.pone.0000877

About the Authors

Hua Wong

Affiliation Laboratoire de Physique Théorique de la Matière Condensée, Université Pierre et Marie Curie, Paris, France

Jean-Marc Victor

Affiliation Laboratoire de Physique Théorique de la Matière Condensée, Université Pierre et Marie Curie, Paris, France

Julien Mozziconacci

*To whom correspondence should be addressed. E-mail: pipo@lptmc.jussieu.fr

Affiliations Laboratoire de Physique Théorique de la Matière Condensée, Université Pierre et Marie Curie, Paris, France, Cell Biology and Biophysics, European Molecular Biology Laboratory, Heidelberg, Germany

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: JM. Performed the experiments: HW. Analyzed the data: JM HW. Contributed reagents/materials/analysis tools: HW. Wrote the paper: JM. Other: Initiated the work: JV. Provided critical comments: JV.

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Nucleosomes
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Histones
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Chromatin
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DNA structure
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Crystal structure
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Electron microscopy
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Kinematics
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DNA-binding proteins
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