Tailor-Made Zinc-Finger Transcription Factors Activate FLO11 Gene Expression with Phenotypic Consequences in the Yeast Saccharomyces cerevisiae

Jia-Ching Shieh; Yu-Che Cheng; Mao-Chang Su; Michael Moore; Yen Choo; Aaron Klug

doi:10.1371/journal.pone.0000746

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Open Access

Peer-reviewed

Research Article

Tailor-Made Zinc-Finger Transcription Factors Activate FLO11 Gene Expression with Phenotypic Consequences in the Yeast Saccharomyces cerevisiae

Jia-Ching Shieh ,

*To whom correspondence should be addressed. E-mail: jcs@csmu.edu.tw

Affiliations Department of Biomedical Sciences, Chung Shan Medical University, Taichung, Taiwan, Medical Research Council Laboratory of Molecular Biology, Cambridge, United Kingdom
⨯
Yu-Che Cheng,

Affiliation Department of Biomedical Sciences, Chung Shan Medical University, Taichung, Taiwan
⨯
Mao-Chang Su,

Affiliation Department of Otorhinolaryngology–Head and Neck Surgery, Chung Shan Medical University Hospital, Taichung, Taiwan
⨯
Michael Moore,

Affiliation Medical Research Council Laboratory of Molecular Biology, Cambridge, United Kingdom
⨯
Yen Choo,

Current address: Plasticell, Media Research Council Technology, London United Kingdom

Affiliation Medical Research Council Laboratory of Molecular Biology, Cambridge, United Kingdom
⨯
Aaron Klug

Affiliation Medical Research Council Laboratory of Molecular Biology, Cambridge, United Kingdom
⨯

Tailor-Made Zinc-Finger Transcription Factors Activate FLO11 Gene Expression with Phenotypic Consequences in the Yeast Saccharomyces cerevisiae

Jia-Ching Shieh,
Yu-Che Cheng,
Mao-Chang Su,
Michael Moore,
Yen Choo,
Aaron Klug

Published: August 15, 2007
https://doi.org/10.1371/journal.pone.0000746

About the Authors

Jia-Ching Shieh

*To whom correspondence should be addressed. E-mail: jcs@csmu.edu.tw

Affiliations Department of Biomedical Sciences, Chung Shan Medical University, Taichung, Taiwan, Medical Research Council Laboratory of Molecular Biology, Cambridge, United Kingdom

Yu-Che Cheng

Affiliation Department of Biomedical Sciences, Chung Shan Medical University, Taichung, Taiwan

Mao-Chang Su

Affiliation Department of Otorhinolaryngology–Head and Neck Surgery, Chung Shan Medical University Hospital, Taichung, Taiwan

Michael Moore

Affiliation Medical Research Council Laboratory of Molecular Biology, Cambridge, United Kingdom

Yen Choo

Current address: Plasticell, Media Research Council Technology, London United Kingdom

Affiliation Medical Research Council Laboratory of Molecular Biology, Cambridge, United Kingdom

Aaron Klug

Affiliation Medical Research Council Laboratory of Molecular Biology, Cambridge, United Kingdom

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: AK YC JS. Performed the experiments: JS YC. Analyzed the data: AK YC JS YC. Contributed reagents/materials/analysis tools: JS YC MS MM. Wrote the paper: JS.

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Saccharomyces cerevisiae
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Cloning
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Gene expression
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Yeast
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DNA transcription
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Glucose
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Phage display
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Phenotypes
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