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Research Article

The Flavonoid Luteolin Worsens Chemical-Induced Colitis in NF-κBEGFP Transgenic Mice through Blockade of NF-κB-Dependent Protective Molecules

  • Thomas Karrasch,

    Affiliation: Department of Medicine and Center for GI Biology and Disease, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

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  • Joo-Sung Kim,

    Affiliation: Department of Medicine and Center for GI Biology and Disease, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

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  • Byung Ik Jang,

    Affiliation: Department of Medicine and Center for GI Biology and Disease, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

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  • Christian Jobin mail

    To whom correspondence should be addressed. E-mail: Job@med.unc.edu

    Affiliation: Department of Medicine and Center for GI Biology and Disease, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

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  • Published: July 04, 2007
  • DOI: 10.1371/journal.pone.0000596

About the Authors

Thomas Karrasch, Joo-Sung Kim, Byung Ik Jang, Christian Jobin
Department of Medicine and Center for GI Biology and Disease, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America

Corresponding Author

Email: Job@med.unc.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: CJ TK. Performed the experiments: TK JK BJ. Analyzed the data: CJ TK. Wrote the paper: CJ TK.