Comprehensive Expression Profiling of Tumor Cell Lines Identifies Molecular Signatures of Melanoma Progression

Byungwoo Ryu; Dave S. Kim; Amena M. DeLuca; Rhoda M. Alani

doi:10.1371/journal.pone.0000594

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Open Access

Peer-reviewed

Research Article

Comprehensive Expression Profiling of Tumor Cell Lines Identifies Molecular Signatures of Melanoma Progression

Byungwoo Ryu ,

*To whom correspondence should be addressed. E-mail: bryu1@jhmi.edu (BR); ralani@jhmi.edu (RMA)

Affiliation The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
⨯
Dave S. Kim,

Affiliation The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
⨯
Amena M. DeLuca,

Affiliation The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
⨯
Rhoda M. Alani

*To whom correspondence should be addressed. E-mail: bryu1@jhmi.edu (BR); ralani@jhmi.edu (RMA)

Affiliation The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
⨯

Comprehensive Expression Profiling of Tumor Cell Lines Identifies Molecular Signatures of Melanoma Progression

Byungwoo Ryu,
Dave S. Kim,
Amena M. DeLuca,
Rhoda M. Alani

Published: July 4, 2007
https://doi.org/10.1371/journal.pone.0000594

About the Authors

Byungwoo Ryu

*To whom correspondence should be addressed. E-mail: bryu1@jhmi.edu (BR); ralani@jhmi.edu (RMA)

Affiliation The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

Dave S. Kim

Affiliation The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

Amena M. DeLuca

Affiliation The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

Rhoda M. Alani

*To whom correspondence should be addressed. E-mail: bryu1@jhmi.edu (BR); ralani@jhmi.edu (RMA)

Affiliation The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: RA BR. Performed the experiments: BR DK AD. Analyzed the data: RA BR DK AD. Contributed reagents/materials/analysis tools: BR. Wrote the paper: RA BR.

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Melanoma
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Melanocytes
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Gene expression
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Melanoma cells
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Transcription factors
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Malignant tumors
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Metastasis
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DNA replication
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