Advertisement
Research Article

Anti-calmodulins and Tricyclic Adjuvants in Pain Therapy Block the TRPV1 Channel

  • Zoltán Oláh mail,

    To whom correspondence should be addressed. E-mail: zolah@brc.hu

    Affiliations: Institute of Biochemistry, Biological Research Center of the Hungarian Academy of Sciences, Szeged, Hungary, Acheuron Hungary Ltd., Szeged, Hungary, Acheuron Pharmaceuticals Inc., San Diego, California, United States of America

    X
  • Katalin Jósvay,

    Affiliation: Institute of Biochemistry, Biological Research Center of the Hungarian Academy of Sciences, Szeged, Hungary

    X
  • László Pecze,

    Affiliation: Institute of Biochemistry, Biological Research Center of the Hungarian Academy of Sciences, Szeged, Hungary

    X
  • Tamás Letoha,

    Affiliations: Department of Medical Chemistry, Faculty of General Medicine, University of Szeged, Szeged, Hungary, Acheuron Hungary Ltd., Szeged, Hungary

    X
  • Norbert Babai,

    Affiliation: Department of Experimental Zoology and Neurobiology, University of Pécs, Pécs, Hungary

    X
  • Dénes Budai,

    Affiliation: Department of Biology, Gyula Juh‡sz Faculty of Education, University of Szeged, Szeged, Hungary

    X
  • Ferenc Ötvös,

    Affiliation: Institute of Biochemistry, Biological Research Center of the Hungarian Academy of Sciences, Szeged, Hungary

    X
  • Sándor Szalma,

    Affiliation: Acheuron Pharmaceuticals Inc., San Diego, California, United States of America

    X
  • Csaba Vizler

    Affiliation: Institute of Biochemistry, Biological Research Center of the Hungarian Academy of Sciences, Szeged, Hungary

    X
  • Published: June 20, 2007
  • DOI: 10.1371/journal.pone.0000545

About the Authors

Zoltán Oláh, Katalin Jósvay, László Pecze, Ferenc Ötvös, Csaba Vizler
Institute of Biochemistry, Biological Research Center of the Hungarian Academy of Sciences, Szeged, Hungary
Zoltán Oláh, Tamás Letoha
Acheuron Hungary Ltd., Szeged, Hungary
Zoltán Oláh, Sándor Szalma
Acheuron Pharmaceuticals Inc., San Diego, California, United States of America
Tamás Letoha
Department of Medical Chemistry, Faculty of General Medicine, University of Szeged, Szeged, Hungary
Norbert Babai
Department of Experimental Zoology and Neurobiology, University of Pécs, Pécs, Hungary
Dénes Budai
Department of Biology, Gyula Juh‡sz Faculty of Education, University of Szeged, Szeged, Hungary

Corresponding Author

Email: zolah@brc.hu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: Cv ZO. Performed the experiments: ZO KJ LP TL NB DB FO SS. Analyzed the data: ZO DB FO SS. Wrote the paper: Cv ZO.