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Research Article

An Open Randomized Comparison of Gatifloxacin versus Cefixime for the Treatment of Uncomplicated Enteric Fever

  • Anil Pandit equal contributor,

    equal contributor Contributed equally to this work with: Anil Pandit, Amit Arjyal

    Affiliation: Patan Hospital, Lagankhel, Lalitpur, Nepal

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  • Amit Arjyal equal contributor,

    equal contributor Contributed equally to this work with: Anil Pandit, Amit Arjyal

    Affiliation: Patan Hospital, Lagankhel, Lalitpur, Nepal

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  • Jeremy N. Day,

    Affiliations: Oxford University Clinical Research Unit, Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam, Centre for Tropical Medicine, Nuffield Department of Clinical Medicine, Oxford University, Oxford, United Kingdom, Regional Infectious Diseases Unit, North Manchester General Hospital, Manchester, United Kingdom

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  • Buddhi Paudyal,

    Affiliation: Patan Hospital, Lagankhel, Lalitpur, Nepal

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  • Sabina Dangol,

    Affiliation: Patan Hospital, Lagankhel, Lalitpur, Nepal

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  • Mark D. Zimmerman,

    Affiliation: Patan Hospital, Lagankhel, Lalitpur, Nepal

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  • Bharat Yadav,

    Affiliation: Patan Hospital, Lagankhel, Lalitpur, Nepal

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  • Kasia Stepniewska,

    Affiliation: Oxford University Clinical Research Unit, Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam

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  • James I. Campbell,

    Affiliations: Oxford University Clinical Research Unit, Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam, Centre for Tropical Medicine, Nuffield Department of Clinical Medicine, Oxford University, Oxford, United Kingdom

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  • Christiane Dolecek,

    Affiliations: Oxford University Clinical Research Unit, Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam, Centre for Tropical Medicine, Nuffield Department of Clinical Medicine, Oxford University, Oxford, United Kingdom

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  • Jeremy J. Farrar,

    Affiliations: Oxford University Clinical Research Unit, Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam, Centre for Tropical Medicine, Nuffield Department of Clinical Medicine, Oxford University, Oxford, United Kingdom

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  • Buddha Basnyat mail

    To whom correspondence should be addressed. E-mail: rishibas@wlink.com.np

    Affiliations: Patan Hospital, Lagankhel, Lalitpur, Nepal, Nepal International Clinic, Kathmandu, Nepal

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  • Published: June 27, 2007
  • DOI: 10.1371/journal.pone.0000542

About the Authors

Anil Pandit, Amit Arjyal, Buddhi Paudyal, Sabina Dangol, Mark D. Zimmerman, Bharat Yadav, Buddha Basnyat
Patan Hospital, Lagankhel, Lalitpur, Nepal
Jeremy N. Day, Kasia Stepniewska, James I. Campbell, Christiane Dolecek, Jeremy J. Farrar
Oxford University Clinical Research Unit, Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam
Jeremy N. Day, James I. Campbell, Christiane Dolecek, Jeremy J. Farrar
Centre for Tropical Medicine, Nuffield Department of Clinical Medicine, Oxford University, Oxford, United Kingdom
Jeremy N. Day
Regional Infectious Diseases Unit, North Manchester General Hospital, Manchester, United Kingdom
Buddha Basnyat
Nepal International Clinic, Kathmandu, Nepal

Corresponding Author

Email: rishibas@wlink.com.np

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: JF BB AP AA JD MZ BY CD BP. Performed the experiments: JF BB AP AA JD SD MZ BY JC CD BP. Analyzed the data: KS. Contributed reagents/materials/analysis tools: JF BB AP AA JD SD MZ BY JC CD BP. Wrote the paper: JF BB AP AA JD MZ BY CD BP. Other: Helped write the paper: JC KS SD.