Short RNA Guides Cleavage by Eukaryotic RNase III

Bruno Lamontagne; Sherif Abou Elela

doi:10.1371/journal.pone.0000472

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Open Access

Peer-reviewed

Research Article

Short RNA Guides Cleavage by Eukaryotic RNase III

Bruno Lamontagne,

Affiliation Groupe ARN (RNA Group), Laboratoire de Génomique Fonctionnelle (Laboratory for Functional Genomics), Département de Microbiologie et d'Infectiologie, Faculté de Médecine et des Sciences de la Santé, Université de Sherbrooke, Sherbrooke, Québec, Canada
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Sherif Abou Elela

*To whom correspondence should be addressed. E-mail: Sherif.Abou.Elela@USherbrooke.ca

Affiliation Groupe ARN (RNA Group), Laboratoire de Génomique Fonctionnelle (Laboratory for Functional Genomics), Département de Microbiologie et d'Infectiologie, Faculté de Médecine et des Sciences de la Santé, Université de Sherbrooke, Sherbrooke, Québec, Canada
⨯

Short RNA Guides Cleavage by Eukaryotic RNase III

Bruno Lamontagne,
Sherif Abou Elela

Published: May 30, 2007
https://doi.org/10.1371/journal.pone.0000472

About the Authors

Bruno Lamontagne

Affiliation Groupe ARN (RNA Group), Laboratoire de Génomique Fonctionnelle (Laboratory for Functional Genomics), Département de Microbiologie et d'Infectiologie, Faculté de Médecine et des Sciences de la Santé, Université de Sherbrooke, Sherbrooke, Québec, Canada

Sherif Abou Elela

*To whom correspondence should be addressed. E-mail: Sherif.Abou.Elela@USherbrooke.ca

Competing Interests

For clarity and transparency we declare a potential duality of interest because we have submitted a patent covering this discovery. However, there is no value for this primary patent submission and we have no reason to believe at this time that the publication will affect neither the potential nor value of the potential patent.

Author Contributions

Conceived and designed the experiments: SA. Performed the experiments: BL. Wrote the paper: SA BL.

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Ribonucleases
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Yeast
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Small nucleolar RNA
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Small nuclear RNA
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Guide RNA
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RNA extraction
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Ribozymes
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Electroporation
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