About the Authors

Jonathan H. Fox

Affiliation Department of Neurology, Harvard Medical School, Massachusetts General Hospital, Charlestown, Massachusetts, United States of America

Jibrin A. Kama

Affiliation Department of Neurology, Harvard Medical School, Massachusetts General Hospital, Charlestown, Massachusetts, United States of America

Gregory Lieberman

Affiliation Department of Neurology, Harvard Medical School, Massachusetts General Hospital, Charlestown, Massachusetts, United States of America

Raman Chopra

Affiliation Department of Neurology, Harvard Medical School, Massachusetts General Hospital, Charlestown, Massachusetts, United States of America

Kate Dorsey

Affiliation Department of Neurology, Harvard Medical School, Massachusetts General Hospital, Charlestown, Massachusetts, United States of America

Vanita Chopra

Affiliation Department of Neurology, Harvard Medical School, Massachusetts General Hospital, Charlestown, Massachusetts, United States of America

Irene Volitakis

Affiliation Oxidation Disorders Laboratory, Mental Health Research Institute of Victoria, and Department of Pathology, The University of Melbourne, Parkville, Victoria, Australia

Robert A. Cherny

Affiliation Oxidation Disorders Laboratory, Mental Health Research Institute of Victoria, and Department of Pathology, The University of Melbourne, Parkville, Victoria, Australia

Ashley I. Bush

Affiliations Genetics and Aging Research Unit, and Department of Psychiatry, Harvard Medical School, Massachusetts General Hospital, Charlestown, Massachusetts, United States of America, Oxidation Disorders Laboratory, Mental Health Research Institute of Victoria, and Department of Pathology, The University of Melbourne, Parkville, Victoria, Australia

Steven Hersch

To whom correspondence should be addressed. E-mail: HERSCH@HELIX.MGH.HARVARD.EDU

Affiliation Department of Neurology, Harvard Medical School, Massachusetts General Hospital, Charlestown, Massachusetts, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed experiments: JHF AIB. Performed ICP-MS metal analyses: IV RAC. Performed all other experiments: JHF JAK. Assisted with mouse experiments: GL RC VC KD. Analyzed data and wrote the paper with contributions from AIB and SH: JHF. Advised experiments and provided most of funding: SH.