About the Authors
- Li Chen
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Affiliation Department of Pathology, Ohio State University Medical Center, Columbus, Ohio, United States of America
- Rulong Shen
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Affiliation Department of Pathology, Ohio State University Medical Center, Columbus, Ohio, United States of America
- Yin Ye
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Affiliation Department of Pathology, Ohio State University Medical Center, Columbus, Ohio, United States of America
- Xin-An Pu
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Affiliation Center for Molecular Neurobiology, Ohio State University Medical Center, Columbus, Ohio, United States of America
- Xingluo Liu
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Affiliation Comprehensive Cancer Center, Ohio State University Medical Center, Columbus, Ohio, United States of America
- Wenrui Duan
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Affiliation Comprehensive Cancer Center, Ohio State University Medical Center, Columbus, Ohio, United States of America
- Jing Wen
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Affiliation Comprehensive Cancer Center, Ohio State University Medical Center, Columbus, Ohio, United States of America
- Jason Zimmerer
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Affiliation Comprehensive Cancer Center, Ohio State University Medical Center, Columbus, Ohio, United States of America
- Ying Wang
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Affiliation Department of Pathology, Ohio State University Medical Center, Columbus, Ohio, United States of America
- Yan Liu
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Affiliation Department of Pathology, Ohio State University Medical Center, Columbus, Ohio, United States of America
- Larry C. Lasky
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Affiliations Department of Pathology, Ohio State University Medical Center, Columbus, Ohio, United States of America, Center for Stem Cell and Regenerative Medicine, Cleveland, Ohio, United States of America
- Nyla A. Heerema
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Affiliations Department of Pathology, Ohio State University Medical Center, Columbus, Ohio, United States of America, Comprehensive Cancer Center, Ohio State University Medical Center, Columbus, Ohio, United States of America
- Danilo Perrotti
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Affiliation Comprehensive Cancer Center, Ohio State University Medical Center, Columbus, Ohio, United States of America
- Keiko Ozato
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Affiliation Laboratory of Molecular Growth Regulation, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, United States of America
- Satomi Kuramochi-Miyagawa
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Affiliation Department of Molecular Cell Biology, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan
- Toru Nakano
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Affiliation Department of Molecular Cell Biology, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan
- Allen J. Yates
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Affiliation Department of Pathology, Ohio State University Medical Center, Columbus, Ohio, United States of America
- William E. Carson III
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Affiliation Comprehensive Cancer Center, Ohio State University Medical Center, Columbus, Ohio, United States of America
- Haifan Lin
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Affiliation Yale Stem Cell Center, Yale University School of Medicine, New Haven, Connecticut, United States of America
- Sanford H. Barsky
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Affiliation Department of Pathology, Ohio State University Medical Center, Columbus, Ohio, United States of America
- Jian-Xin Gao
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*To whom correspondence should be addressed. E-mail: Jian-Xin.Gao@osumc.edu
Affiliations Department of Pathology, Ohio State University Medical Center, Columbus, Ohio, United States of America, Comprehensive Cancer Center, Ohio State University Medical Center, Columbus, Ohio, United States of America
Competing Interests
The authors have declared that no competing interests exist.
Author Contributions
Conceived and designed the experiments: JG. Performed the experiments: YL HL JG LC YY XP JW YW NH DP. Analyzed the data: JG LC RS NH DP. Contributed reagents/materials/analysis tools: HL JG XL WD LL KO SK TN SB JZ AY WC. Wrote the paper: JG. Other: Discussed experiments and reviewed manuscript: HL. Adoptive transfer, RNAi, RT-PCR, DNA PCR: LC. Reviewed all the histopathologcial and immunohistotological slides: RS. Constructed lentiviral vectors: YY. Generated precancerous stem cell chimera mice: XP. CFC assay: JW. Karyotyping: NH. The mentor of Dr. Yin Ye: SB.