A Practical Genome Scan for Population-Specific Strong Selective Sweeps That Have Reached Fixation

Ryosuke Kimura; Akihiro Fujimoto; Katsushi Tokunaga; Jun Ohashi

doi:10.1371/journal.pone.0000286

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Open Access

Peer-reviewed

Research Article

A Practical Genome Scan for Population-Specific Strong Selective Sweeps That Have Reached Fixation

Ryosuke Kimura ,

*To whom correspondence should be addressed. E-mail: rkimura@m.u-tokyo.ac.jp

Affiliations Department of Human Genetics, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan, Japan Society for the Promotion of Science, Tokyo, Japan
⨯
Akihiro Fujimoto,

Affiliation Department of Human Genetics, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
⨯
Katsushi Tokunaga,

Affiliation Department of Human Genetics, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
⨯
Jun Ohashi

Affiliation Department of Human Genetics, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
⨯

A Practical Genome Scan for Population-Specific Strong Selective Sweeps That Have Reached Fixation

Ryosuke Kimura,
Akihiro Fujimoto,
Katsushi Tokunaga,
Jun Ohashi

Published: March 14, 2007
https://doi.org/10.1371/journal.pone.0000286

About the Authors

Ryosuke Kimura

*To whom correspondence should be addressed. E-mail: rkimura@m.u-tokyo.ac.jp

Affiliations Department of Human Genetics, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan, Japan Society for the Promotion of Science, Tokyo, Japan

Akihiro Fujimoto

Affiliation Department of Human Genetics, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan

Katsushi Tokunaga

Affiliation Department of Human Genetics, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan

Jun Ohashi

Affiliation Department of Human Genetics, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: RK KT JO. Performed the experiments: RK JO. Analyzed the data: RK AF JO. Contributed reagents/materials/analysis tools: RK KT JO. Wrote the paper: RK JO.

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Haplotypes
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Single nucleotide polymorphisms
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Homozygosity
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Genetic loci
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Natural selection
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Human genomics
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Test statistics
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Population genetics
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