About the Authors

Arja Kaipainen

Affiliation Vascular Biology Program, Department of Surgery, Children's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

Mark W. Kieran

Affiliations Vascular Biology Program, Department of Surgery, Children's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America, Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, United States of America

Sui Huang

Affiliation Vascular Biology Program, Department of Surgery, Children's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

Catherine Butterfield

Affiliation Vascular Biology Program, Department of Surgery, Children's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

Diane Bielenberg

Affiliation Vascular Biology Program, Department of Surgery, Children's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

Gustavo Mostoslavsky

Affiliation Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America

Richard Mulligan

Affiliation Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America

Judah Folkman

Affiliation Vascular Biology Program, Department of Surgery, Children's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

Dipak Panigrahy

To whom correspondence should be addressed. E-mail: dipak.panigrahy@childrens.harvard.edu

Affiliation Vascular Biology Program, Department of Surgery, Children's Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SH DP AK. Performed the experiments: SH DP AK. Analyzed the data: SH DP AK. Contributed reagents/materials/analysis tools: SH. Wrote the paper: SH DP AK. Other: Participated in designing the studies and data analysis and participated in the intellectual input and discussions with AK and DP, and contributed to the writing of the paper: JF. Participated in designing the studies and data analysis and participated in the intellectual input and discussions with AK and DP and contributed to the writing of the paper: SH. Participated in designing all bone marrow transplantation and antibody depletion studies and performed the and contributed to the writing of the paper: GM. Participated in data analysis and the intellectual input and discussions with AK and DP: MK. Participated in designing the corneal assays and performed them: CB. Participated in designing all the metastasis assays and performed them: DB. Participated in designing the bone marrow transplantation experiments and the intellectual input and discussions with GM: RM.