Meta-Analysis in Genome-Wide Association Datasets: Strategies and Application in Parkinson Disease

Evangelos Evangelou; Demetrius M. Maraganore; John P.A. Ioannidis

doi:10.1371/journal.pone.0000196

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Open Access

Peer-reviewed

Research Article

Meta-Analysis in Genome-Wide Association Datasets: Strategies and Application in Parkinson Disease

Evangelos Evangelou,

Affiliation Clinical and Molecular Epidemiology Unit, Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina, Greece
⨯
Demetrius M. Maraganore,

Affiliation Department of Neurology, Mayo Clinic College of Medicine, Rochester, Minnesota, United States of America
⨯
John P.A. Ioannidis

*To whom correspondence should be addressed. E-mail: jioannid@cc.uoi.gr

Affiliations Clinical and Molecular Epidemiology Unit, Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina, Greece, Biomedical Research Institute, Foundation for Research and Technology-Hellas, Ioannina, Greece, Institute for Clinical Research and Health Policy Studies, Tufts-New England Medical Center, Tufts University School of Medicine, Boston, Massachusetts, United States of America
⨯

Meta-Analysis in Genome-Wide Association Datasets: Strategies and Application in Parkinson Disease

Evangelos Evangelou,
Demetrius M. Maraganore,
John P.A. Ioannidis

Published: February 7, 2007
https://doi.org/10.1371/journal.pone.0000196

About the Authors

Evangelos Evangelou

Affiliation Clinical and Molecular Epidemiology Unit, Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina, Greece

Demetrius M. Maraganore

Affiliation Department of Neurology, Mayo Clinic College of Medicine, Rochester, Minnesota, United States of America

John P.A. Ioannidis

*To whom correspondence should be addressed. E-mail: jioannid@cc.uoi.gr

Affiliations Clinical and Molecular Epidemiology Unit, Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina, Greece, Biomedical Research Institute, Foundation for Research and Technology-Hellas, Ioannina, Greece, Institute for Clinical Research and Health Policy Studies, Tufts-New England Medical Center, Tufts University School of Medicine, Boston, Massachusetts, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: JI DM EE. Performed the experiments: DM. Analyzed the data: JI EE. Wrote the paper: JI DM EE.

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Single nucleotide polymorphisms
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Metaanalysis
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Genome-wide association studies
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Parkinson disease
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Statistical data
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Genotyping
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Genetics
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Genetics of disease
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