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Research Article

Heterologous Tissue Culture Expression Signature Predicts Human Breast Cancer Prognosis

  • Eun Sung Park mail,

    To whom correspondence should be addressed. E-mail: parkeu@mail.nih.gov (ESP); jm8p@nih.gov (JFM)

    Affiliation: Laboratory of Genetics, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America

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  • Ju-Seog Lee,

    Affiliation: Laboratory of Experimental Carcinogenesis, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America

    Current address: M.D. Anderson Cancer Center, Houston, Texas, United States of America

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  • Hyun Goo Woo,

    Affiliation: Laboratory of Experimental Carcinogenesis, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America

    X
  • Fenghuang Zhan,

    Affiliation: Donna and Donald Lambert Laboratory of Myeloma Genetics, Myeloma Institute for Research and Therapy, University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States of America

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  • Joanna H. Shih,

    Affiliation: Biometric Research Branch, Division of Cancer Treatment and Diagnosis, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America

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  • John D. Shaughnessy Jr.,

    Affiliation: Donna and Donald Lambert Laboratory of Myeloma Genetics, Myeloma Institute for Research and Therapy, University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States of America

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  • J. Frederic Mushinski mail

    To whom correspondence should be addressed. E-mail: parkeu@mail.nih.gov (ESP); jm8p@nih.gov (JFM)

    Affiliation: Laboratory of Genetics, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America

    X
  • Published: January 03, 2007
  • DOI: 10.1371/journal.pone.0000145

About the Authors

Eun Sung Park, J. Frederic Mushinski
Laboratory of Genetics, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America
Ju-Seog Lee, Hyun Goo Woo
Laboratory of Experimental Carcinogenesis, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America
Joanna H. Shih
Biometric Research Branch, Division of Cancer Treatment and Diagnosis, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America
Fenghuang Zhan, John D. Shaughnessy Jr.
Donna and Donald Lambert Laboratory of Myeloma Genetics, Myeloma Institute for Research and Therapy, University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States of America

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: JM EP JL JL. Performed the experiments: FZ. Analyzed the data: EP JL HW JL. Contributed reagents/materials/analysis tools: JS JM. Wrote the paper: JM EP. Other: Reviewed the statistical analysis: JS.