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Research Article

IL-7 Up-Regulates TNF-α-Dependent Osteoclastogenesis in Patients Affected by Solid Tumor

  • Ilaria Roato mail,

    To whom correspondence should be addressed. E-mail: roato78@libero.it

    Affiliations: Center for Experimental Research and Medical Studies (CeRMS), University and AZO San Giovanni Battista, Turin, Italy, Department of Medical Oncology, University and AZO San Giovanni Battista, Turin, Italy

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  • Giacomina Brunetti,

    Affiliation: Department of Human Anatomy and Histology, University of Bari, Bari, Italy

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  • Eva Gorassini,

    Affiliation: Center for Experimental Research and Medical Studies (CeRMS), University and AZO San Giovanni Battista, Turin, Italy

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  • Maria Grano,

    Affiliation: Department of Human Anatomy and Histology, University of Bari, Bari, Italy

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  • Silvia Colucci,

    Affiliation: Department of Human Anatomy and Histology, University of Bari, Bari, Italy

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  • Lisa Bonello,

    Affiliation: Center for Experimental Research and Medical Studies (CeRMS), University and AZO San Giovanni Battista, Turin, Italy

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  • Lucio Buffoni,

    Affiliation: Department of Medical Oncology, University and AZO San Giovanni Battista, Turin, Italy

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  • Roberto Manfredi,

    Affiliation: Department of Medical Oncology, Ospedale Civile, Asti, Italy

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  • Enrico Ruffini,

    Affiliation: Department of Toracic Surgery, AZO San Giovanni Battista, Turin, Italy

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  • Davide Ottaviani,

    Affiliation: Department of Medical Oncology, University and AZO San Giovanni Battista, Turin, Italy

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  • Libero Ciuffreda,

    Affiliation: Department of Medical Oncology, University and AZO San Giovanni Battista, Turin, Italy

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  • Antonio Mussa,

    Affiliation: Department of Medical Oncology, University and AZO San Giovanni Battista, Turin, Italy

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  • Riccardo Ferracini

    Affiliation: Department of Orthopaedics, AZO San Giovanni Battista, Turin, Italy

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  • Published: December 27, 2006
  • DOI: 10.1371/journal.pone.0000124

About the Authors

Ilaria Roato, Eva Gorassini, Lisa Bonello
Center for Experimental Research and Medical Studies (CeRMS), University and AZO San Giovanni Battista, Turin, Italy
Giacomina Brunetti, Maria Grano, Silvia Colucci
Department of Human Anatomy and Histology, University of Bari, Bari, Italy
Ilaria Roato, Lucio Buffoni, Davide Ottaviani, Libero Ciuffreda, Antonio Mussa
Department of Medical Oncology, University and AZO San Giovanni Battista, Turin, Italy
Roberto Manfredi
Department of Medical Oncology, Ospedale Civile, Asti, Italy
Enrico Ruffini
Department of Toracic Surgery, AZO San Giovanni Battista, Turin, Italy
Riccardo Ferracini
Department of Orthopaedics, AZO San Giovanni Battista, Turin, Italy

Corresponding Author

Email: roato78@libero.it

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: IR RF. Performed the experiments: IR EG LB. Analyzed the data: IR GB EG MG SC RF. Contributed reagents/materials/analysis tools: LB RM ER DO LC AM. Wrote the paper: IR GB MG RF.