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Research Article

Efficient Non-Viral Ocular Gene Transfer with Compacted DNA Nanoparticles

  • Rafal Farjo,

    Affiliation: Department of Cell Biology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States of America

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  • Jeff Skaggs,

    Affiliation: Department of Cell Biology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States of America

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  • Alexander B. Quiambao,

    Affiliation: Department of Cell Biology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States of America

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  • Mark J. Cooper,

    Affiliation: Copernicus Therapeutics, Inc., Cleveland, Ohio, United States of America

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  • Muna I. Naash mail

    To whom correspondence should be addressed. E-mail: muna-naash@ouhsc.edu

    Affiliation: Department of Cell Biology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States of America

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  • Published: December 20, 2006
  • DOI: 10.1371/journal.pone.0000038

About the Authors

Rafal Farjo, Jeff Skaggs, Alexander B. Quiambao, Muna I. Naash
Department of Cell Biology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States of America
Mark J. Cooper
Copernicus Therapeutics, Inc., Cleveland, Ohio, United States of America

Corresponding Author

Email: muna-naash@ouhsc.edu

Competing Interests

MJC is Senior VP Science & Medical Affairs for Copernicus Therapeutics, Inc.

Author Contributions

Conceived and designed the experiments: MN RF. Performed the experiments: RF JS AQ. Analyzed the data: MN RF. Contributed reagents/materials/analysis tools: MC. Wrote the paper: MN RF MC.