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Research Article

Restructuring of Pancreatic Islets and Insulin Secretion in a Postnatal Critical Window

  • Cristina Aguayo-Mazzucato,

    Affiliation: Department of Biophysics, Institute of Cellular Physiology, National Autonomous University of México, Mexico City, Mexico

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  • Carmen Sanchez-Soto,

    Affiliation: Department of Biophysics, Institute of Cellular Physiology, National Autonomous University of México, Mexico City, Mexico

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  • Victoria Godinez-Puig,

    Affiliation: Faculty of Medicine, National Autonomous University of Mexico, Mexico City, Mexico

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  • Gabriel Gutiérrez-Ospina,

    Affiliation: Department of Cell Biology and Physiology, Biomedical Research Institute, National Autonomous University of México, Mexico City, Mexico

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  • Marcia Hiriart mail

    To whom correspondence should be addressed. E-mail: mhiriart@ifc.unam.mx

    Affiliation: Department of Biophysics, Institute of Cellular Physiology, National Autonomous University of México, Mexico City, Mexico

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  • Published: December 20, 2006
  • DOI: 10.1371/journal.pone.0000035

About the Authors

Cristina Aguayo-Mazzucato, Carmen Sanchez-Soto, Marcia Hiriart
Department of Biophysics, Institute of Cellular Physiology, National Autonomous University of México, Mexico City, Mexico
Gabriel Gutiérrez-Ospina
Department of Cell Biology and Physiology, Biomedical Research Institute, National Autonomous University of México, Mexico City, Mexico
Victoria Godinez-Puig
Faculty of Medicine, National Autonomous University of Mexico, Mexico City, Mexico

Corresponding Author

Email: mhiriart@ifc.unam.mx

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: MH CA GG. Performed the experiments: MH CA CS VG. Analyzed the data: MH CA CS VG GG. Contributed reagents/materials/analysis tools: MH CA GG. Wrote the paper: MH CA GG.