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Research Article

Dissecting Oct3/4-Regulated Gene Networks in Embryonic Stem Cells by Expression Profiling

  • Ryo Matoba,

    Affiliation: Developmental Genomics and Aging Section, Laboratory of Genetics, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, United States of America

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  • Hitoshi Niwa,

    Affiliation: Laboratory of Pluripotent Cell Studies, RIKEN Center for Developmental Biology, Kobe, Japan

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  • Shinji Masui,

    Affiliation: Laboratory of Pluripotent Cell Studies, RIKEN Center for Developmental Biology, Kobe, Japan

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  • Satoshi Ohtsuka,

    Affiliation: Laboratory of Pluripotent Cell Studies, RIKEN Center for Developmental Biology, Kobe, Japan

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  • Mark G. Carter,

    Affiliation: Developmental Genomics and Aging Section, Laboratory of Genetics, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, United States of America

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  • Alexei A. Sharov,

    Affiliation: Developmental Genomics and Aging Section, Laboratory of Genetics, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, United States of America

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  • Minoru S.H. Ko mail

    To whom correspondence should be addressed. E-mail: kom@mail.nih.gov

    Affiliation: Developmental Genomics and Aging Section, Laboratory of Genetics, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, United States of America

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  • Published: December 20, 2006
  • DOI: 10.1371/journal.pone.0000026

About the Authors

Ryo Matoba, Mark G. Carter, Alexei A. Sharov, Minoru S.H. Ko
Developmental Genomics and Aging Section, Laboratory of Genetics, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, United States of America
Hitoshi Niwa, Shinji Masui, Satoshi Ohtsuka
Laboratory of Pluripotent Cell Studies, RIKEN Center for Developmental Biology, Kobe, Japan

Corresponding Author

Email: kom@mail.nih.gov

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: MK RM HN. Performed the experiments: MC RM HN SM SO. Analyzed the data: MK AS RM HN. Wrote the paper: MK RM