Expression of Transgenes Targeted to the Gt(ROSA)26Sor Locus Is Orientation Dependent

Douglas Strathdee; Helen Ibbotson; Seth G. N. Grant

doi:10.1371/journal.pone.0000004

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Open Access

Peer-reviewed

Research Article

Expression of Transgenes Targeted to the Gt(ROSA)26Sor Locus Is Orientation Dependent

Douglas Strathdee ,

*To whom correspondence should be addressed. E-mail: ds10@sanger.ac.uk

Affiliations The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom, Centre for Neuroscience Research, University of Edinburgh, Edinburgh, Scotland
⨯
Helen Ibbotson,

Affiliation Centre for Neuroscience Research, University of Edinburgh, Edinburgh, Scotland
⨯
Seth G. N. Grant

Affiliations The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom, Centre for Neuroscience Research, University of Edinburgh, Edinburgh, Scotland
⨯

Expression of Transgenes Targeted to the Gt(ROSA)26Sor Locus Is Orientation Dependent

Douglas Strathdee,
Helen Ibbotson,
Seth G. N. Grant

Published: December 20, 2006
https://doi.org/10.1371/journal.pone.0000004

About the Authors

Douglas Strathdee

*To whom correspondence should be addressed. E-mail: ds10@sanger.ac.uk

Affiliations The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom, Centre for Neuroscience Research, University of Edinburgh, Edinburgh, Scotland

Helen Ibbotson

Affiliation Centre for Neuroscience Research, University of Edinburgh, Edinburgh, Scotland

Seth G. N. Grant

Affiliations The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, United Kingdom, Centre for Neuroscience Research, University of Edinburgh, Edinburgh, Scotland

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SG DS. Performed the experiments: DS HI. Analyzed the data: DS. Wrote the paper: SG DS

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Selectable markers
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Genetic loci
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Gene expression
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Doxycycline
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Cloning
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