About the Authors

Rui Yang

Contributed equally to this work with: Rui Yang, Lan Guo

Affiliation Department of Orthopedics, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, People's Republic of China

Lan Guo

Contributed equally to this work with: Rui Yang, Lan Guo

Affiliation Department of Medical Statistics and Epidemiology, School of Public Health, Sun Yat-sen University, Guangzhou, People's Republic of China

Peng Wang

Affiliation Department of Orthopedics, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, People's Republic of China

Lin Huang

Affiliation Department of Orthopedics, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, People's Republic of China

Yong Tang

Affiliation Department of Orthopedics, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, People's Republic of China

Wenhao Wang

Affiliation Department of Orthopedics, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, People's Republic of China

Keng Chen

Affiliation Department of Orthopedics, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, People's Republic of China

Jichao Ye

Affiliation Department of Orthopedics, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, People's Republic of China

Ciyong Lu

Affiliation Department of Medical Statistics and Epidemiology, School of Public Health, Sun Yat-sen University, Guangzhou, People's Republic of China

Yanfeng Wu

wuyanfengcn@126.com (YFW); shenh.y.@163.com (HYS)

These authors also contributed equally to this work.

Affiliation Biotherapy Centre, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, People's Republic of China

Huiyong Shen

wuyanfengcn@126.com (YFW); shenh.y.@163.com (HYS)

These authors also contributed equally to this work.

Affiliation Department of Orthopedics, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, People's Republic of China

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: RY LG HYS YFW. Performed the experiments: RY LG HYS YFW PW LH YT WHW KC JCY CYL. Analyzed the data: RY LG. Contributed reagents/materials/analysis tools: RY LG. Wrote the paper: RY LG. Conceived the study, participated in its design and helped to draft the manuscript: RY LG. Participated in article revision and academic counseling: PW LH YT WHW KC JCY CL YFW HYS. Read and approved the final manuscript: RY LG PW LH YT WHW KC JCY CL YFW HYS.