About the Authors
- Jens H. Westhoff
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* E-mail: jens.westhoff@med.uni-heidelberg.de (JHW); urban.liebel@kit.edun (UL); jochen.gehrig@kit.edu (JG)
Affiliation Department of Pediatrics I, University Children’s Hospital, University of Heidelberg, Heidelberg, Germany
- Stefan Giselbrecht
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Affiliation Institute for Biological Interfaces 2, Karlsruhe Institute of Technology, Eggenstein-Leopoldshafen, Germany
- Miriam Schmidts
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Affiliation Molecular Medicine Unit, Birth Defects Research Centre, University College London (UCL), Institute of Child Health, London, United Kingdom
- Sebastian Schindler
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Affiliation Department of Pediatrics I, University Children’s Hospital, University of Heidelberg, Heidelberg, Germany
- Philip L. Beales
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Affiliation Molecular Medicine Unit, Birth Defects Research Centre, University College London (UCL), Institute of Child Health, London, United Kingdom
- Burkhard Tönshoff
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Affiliation Department of Pediatrics I, University Children’s Hospital, University of Heidelberg, Heidelberg, Germany
- Urban Liebel
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* E-mail: jens.westhoff@med.uni-heidelberg.de (JHW); urban.liebel@kit.edun (UL); jochen.gehrig@kit.edu (JG)
Affiliations Institute for Applied Computer Science, Karlsruhe Institute of Technology, Eggenstein-Leopoldshafen, Germany, Accelerator Laboratory, Innovation Department, Karlsruhe Institute of Technology, Eggenstein-Leopoldshafen, Germany;
- Jochen Gehrig
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* E-mail: jens.westhoff@med.uni-heidelberg.de (JHW); urban.liebel@kit.edun (UL); jochen.gehrig@kit.edu (JG)
Affiliations Institute of Toxicology and Genetics, Karlsruhe Institute of Technology, Eggenstein-Leopoldshafen, Germany, Accelerator Laboratory, Innovation Department, Karlsruhe Institute of Technology, Eggenstein-Leopoldshafen, Germany;
Competing Interests
The authors have the following conflicts. UL is co-founder and executive director, and JG is application strategist at Acquifer GmbH. There are no patents, products in development or marketed products to declare. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.
Author Contributions
Conceived and designed the experiments: JHW JG SG MS PLB. Performed the experiments: SS JHW JG MS. Analyzed the data: JHW SS MS JG. Contributed reagents/materials/analysis tools: SG. Wrote the manuscript: JHW JG MS. Designed the orientation tool: SG JG. Generated data handling and visualization tools: JG. Designed morpholino injections experiments: MS PLB. Designed the study: JHW JG. Supervised the study: JHW JG UL. Gave general advice and edited the manuscript: BT.