About the Authors
- Masaki Takahashi
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Affiliation Department of Molecular Pharmacology, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Kodaira, Tokyo, Japan
- Tomoko Chiyo
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Affiliation Department of Molecular Therapy, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Kodaira, Tokyo, Japan
- Takashi Okada
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Affiliation Department of Molecular Therapy, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Kodaira, Tokyo, Japan
- Hirohiko Hohjoh
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* E-mail: hohjohh@ncnp.go.jp
Affiliation Department of Molecular Pharmacology, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Kodaira, Tokyo, Japan
Competing Interests
Drs. Hohjoh and Takahashi have a pending patent regarding siRNAs designed in this study. Title of Invention: AGENT FOR SUPPRESSING EXPRESSION OF DOMINANT MUTANT GENE No. of Invention: WO2012043633 A1. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.
Author Contributions
Conceived and designed the experiments: HH MT. Performed the experiments: MT TC HH. Analyzed the data: MT HH. Contributed reagents/materials/analysis tools: HH TO. Wrote the manuscript: MT HH.