Corticosteroid-Binding Globulin: Structure-Function Implications from Species Differences

Bernd R. Gardill; Michael R. Vogl; Hai-Yan Lin; Geoffrey L. Hammond; Yves A. Muller

doi:10.1371/journal.pone.0052759

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Open Access

Peer-reviewed

Research Article

Corticosteroid-Binding Globulin: Structure-Function Implications from Species Differences

Bernd R. Gardill,

Affiliation Department of Biology, Lehrstuhl für Biotechnik, Friedrich-Alexander-University Erlangen-Nuremberg, Erlangen, Germany
⨯
Michael R. Vogl,

Affiliation Department of Biology, Lehrstuhl für Biotechnik, Friedrich-Alexander-University Erlangen-Nuremberg, Erlangen, Germany
⨯
Hai-Yan Lin,

Affiliation State Key Laboratory of Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China
⨯
Geoffrey L. Hammond,

Affiliation Department of Obstetrics and Gynecology, Child and Family Research Institute, University of British Columbia, Vancouver, British Columbia, Canada
⨯
Yves A. Muller

* E-mail: ymuller@biologie.uni-erlangen.de

Affiliation Department of Biology, Lehrstuhl für Biotechnik, Friedrich-Alexander-University Erlangen-Nuremberg, Erlangen, Germany
⨯

Corticosteroid-Binding Globulin: Structure-Function Implications from Species Differences

Bernd R. Gardill,
Michael R. Vogl,
Hai-Yan Lin,
Geoffrey L. Hammond,
Yves A. Muller

Published: December 26, 2012
https://doi.org/10.1371/journal.pone.0052759

About the Authors

Bernd R. Gardill

Affiliation Department of Biology, Lehrstuhl für Biotechnik, Friedrich-Alexander-University Erlangen-Nuremberg, Erlangen, Germany

Michael R. Vogl

Affiliation Department of Biology, Lehrstuhl für Biotechnik, Friedrich-Alexander-University Erlangen-Nuremberg, Erlangen, Germany

Hai-Yan Lin

Affiliation State Key Laboratory of Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China

Geoffrey L. Hammond

Affiliation Department of Obstetrics and Gynecology, Child and Family Research Institute, University of British Columbia, Vancouver, British Columbia, Canada

Yves A. Muller

* E-mail: ymuller@biologie.uni-erlangen.de

Affiliation Department of Biology, Lehrstuhl für Biotechnik, Friedrich-Alexander-University Erlangen-Nuremberg, Erlangen, Germany

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: BRG MRV GLH YAM. Performed the experiments: BRG MRV YAM. Analyzed the data: BRG HYL GLH YAM. Wrote the paper: BRG GLH YAM.

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Crystal structure
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Cortisol
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Progesterone
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Rats
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Neutrophils
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Steroids
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Thermal stability
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Electron density
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