About the Authors

John Archer

Contributed equally to this work with: John Archer, Jan Weber

Affiliation Computational and Evolutionary Biology, Faculty of Life Sciences, The University of Manchester, Manchester, United Kingdom

Jan Weber

Contributed equally to this work with: John Archer, Jan Weber

Affiliation Institute of Organic Chemistry and Biochemistry, Prague, Czech Republic

Kenneth Henry

Affiliation Division of Infectious Diseases, Case Western Reserve University, Cleveland, Ohio, United States of America

Dane Winner

Affiliation Department of Pathology, Case Western Reserve University, Cleveland, Ohio, United States of America

Richard Gibson

Affiliation Division of Infectious Diseases, Case Western Reserve University, Cleveland, Ohio, United States of America

Lawrence Lee

Affiliation Pacific Biosciences, Menlo Park, California, United States of America

Ellen Paxinos

Affiliation Pacific Biosciences, Menlo Park, California, United States of America

Eric J. Arts

Affiliation Division of Infectious Diseases, Case Western Reserve University, Cleveland, Ohio, United States of America

David L. Robertson

Affiliation Computational and Evolutionary Biology, Faculty of Life Sciences, The University of Manchester, Manchester, United Kingdom

Larry Mimms

Affiliation Quidel Corporation, San Diego, California, United States of America

Miguel E. Quiñones-Mateu

meq@case.edu

Affiliations Department of Pathology, Case Western Reserve University, Cleveland, Ohio, United States of America, University Hospital Translational Laboratory, University Hospitals Case Medical Center, Cleveland, Ohio, United States of America

Competing Interests

JA, JW, KH, DW, RG, EJA, DLR, and MEQ-M report no conflict of interest. LL and EP are employed by Pacific Biosciences. LM is employed by Quidel Corporation. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: MEQ-M LM. Performed the experiments: JW KH DW RG LL. Analyzed the data: JA DLR MEQ-M. Wrote the paper: MEQ-M. Provided access to material, technology and critical advice: EP EJA LM.